Evidence map›Paper›PMID 34835171›Full record

ArticleVaccines2021

Broad-Spectrum and Gram-Negative-Targeting Antibiotics Differentially Regulate Antibody Isotype Responses to Injected Vaccines.

Aklilu F Haile, Rachel M Woodfint, Eunsoo Kim, Marisa R Joldrichsen, Nega Berhe, Wondwoossen A Gebreyes, Prosper N Boyaka

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Vaccines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Aklilu F HaileDepartment of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210, USA.
Rachel M WoodfintDepartment of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210, USA.
Eunsoo KimDepartment of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0003-4196-8280
Marisa R JoldrichsenDepartment of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210, USA.
Nega BerheAklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa 1000, Ethiopia.
Wondwoossen A GebreyesDepartment of Preventive Medicine, The Ohio State University, Columbus, OH 43210, USA.
Prosper N BoyakaDepartment of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210, USA.
The Ohio State University · USAddis Ababa University · ET

Funding

Host Responses to the Pore-Forming Toxin Listeriolysin OR01AI157205 · NIAID · OHIO STATE UNIVERSITY · PI AMER, AMAL O, BOYAKA, PROSPER N · 2021 to 2025
$3.2M
Targeting myeloid cells for regulation of alum-based immunityR01AI145144 · NIAID · OHIO STATE UNIVERSITY · PI BOYAKA, PROSPER N · 2020 to 2024
$3.1M
A novel lactic acid bacteria-based norovirus vaccineR01AI123661 · NIAID · OHIO STATE UNIVERSITY · PI BOYAKA, PROSPER N, HE, XIAOMING · 2016 to 2020
$3.0M
Regulation of mucosal IgA and allergic inflammation by intestinal epithelial cellsR01DK101323 · NIDDK · OHIO STATE UNIVERSITY · PI BOYAKA, PROSPER N · 2015 to 2019
$1.7M
Short Trem Research Training for Veterinary StudentsT35OD010977 · OD · OHIO STATE UNIVERSITY · PI Christine A Petersen · 2012 to 2026
$1.1M
NIAID NIH HHS R01 AI123661NIAID NIH HHS R01 AI145144NIAID NIH HHS R01 AI157205NIDDK NIH HHS R01 DK101323NIH HHS R01 AI18958, R01 DK101323, and R01AI1451NIH HHS T35 OD010977
6 · The paper itself

Abstract

Antibiotics are extensively used worldwide for the treatment of common infections by agents such as

Indexed as

antibioticsIgA responsesvaccines

Identifiers

PMID34835171
PMCPMC8619726
OpenAlexW3211172519

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.