Evidence map›Paper›PMID 34835153›Full record

ArticleVaccines2021

Pfizer-BioNTech and Sinopharm: A Comparative Study on Post-Vaccination Antibody Titers.

Rami Alqassieh, Aiman Suleiman, Sami Abu-Halaweh, Abeer Santarisi, Omar Shatnawi, Lara Shdaifat, Amjed Tarifi, Mohammad Al-Tamimi, Abdel-Ellah Al-Shudifat, Heba Alsmadi and 7 more

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Immunoglobulin G and neutralizing antibody response after CoronaVac.Revista da Associacao Medica Brasileira (1992) · 2026
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  5. Observational
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  12. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 2 countries.

Rami AlqassiehDepartment of General and Specialized Surgery, Faculty of Medicine, The Hashemite University, Zarqa 13133, Jordan.ORCID 0000-0002-0270-0436
Aiman SuleimanBeth Israel Deaconess Medical Center, Anesthesia and Intensive Care Department, Harvard Medical School, Boston, MA 02215, USA.ORCID 0000-0003-2625-4028
Sami Abu-HalawehDepartment of Anesthesia and Intensive Care, School of Medicine, The University of Jordan, Amman 11942, Jordan.
Abeer SantarisiDepartment of Emergency Medicine and Accidents, School of Medicine, The University of Jordan, Amman 11942, Jordan.
Omar ShatnawiDepartment of Cancer Biology, Wake Forest School of Medicine and Wake Forest Baptist Health, Winston-Salem, NC 27157, USA.ORCID 0000-0002-2304-8969
Lara ShdaifatSchool of Medicine, Mutah University, Karak 61710, Jordan.
Amjed TarifiDepartment of General and Specialized Surgery, Faculty of Medicine, The Hashemite University, Zarqa 13133, Jordan.ORCID 0000-0001-8519-9431
Mohammad Al-TamimiFaculty of Medicine, The Hashemite University, Zarqa 13133, Jordan.ORCID 0000-0001-7486-4192
Abdel-Ellah Al-ShudifatFaculty of Medicine, The Hashemite University, Zarqa 13133, Jordan.
Heba AlsmadiDepartment of Anesthesia and Intensive Care, School of Medicine, The University of Jordan, Amman 11942, Jordan.
Ahmed Al SharqawiDepartment of Anesthesia and Intensive Care, School of Medicine, The University of Jordan, Amman 11942, Jordan.
Hadeel AlnawaisehDepartment of Anesthesia and Intensive Care, School of Medicine, The University of Jordan, Amman 11942, Jordan.
Yara AnaswehDepartment of Anesthesia and Intensive Care, School of Medicine, The University of Jordan, Amman 11942, Jordan.
Farah Abo DomaidahDepartment of Anesthesia and Intensive Care, School of Medicine, The University of Jordan, Amman 11942, Jordan.
Haneen Abu JaberDepartment of Anesthesia and Intensive Care, School of Medicine, The University of Jordan, Amman 11942, Jordan.
Mohammad Rashid Al-ZarirDepartment of Anesthesia and Intensive Care, School of Medicine, The University of Jordan, Amman 11942, Jordan.
Isam BsisuDepartment of Anesthesia and Intensive Care, School of Medicine, The University of Jordan, Amman 11942, Jordan.ORCID 0000-0002-8999-8334
University of Jordan · JOHashemite University · JOAtrium Health Wake Forest Baptist · USBeth Israel Deaconess Medical Center · USMutah University · JO

Funding

Deanship of Scientific Research at the Hashemite University 639/2021
6 · The paper itself

Abstract

COVID-19 (coronavirus disease 2019) vaccines induce immunity through different mechanisms. The aim of this study is to compare the titers of specific antibodies in subjects vaccinated with either the Pfizer-BioNTech COVID-19 vaccine or the Sinopharm vaccine. This prospective observational cohort included Jordanian adults vaccinated with two doses, 21 days apart, of either of the two aforementioned vaccines. Titers were collected 6 weeks after the administration of the second dose. Overall, 288 participants were included, of which 141 were administered the Pfizer-BioNTech vaccine, while 147 were administered the Sinopharm vaccine. Remarkably, 140 (99.3%) of the Pfizer-BioNTech vaccine recipients had positive IgG titers, while 126 (85.7%) of Sinopharm recipients had positive IgG (

Indexed as

antibodyCOVID-19Pfizer-BioNTechSinopharmtitersvaccine

Identifiers

PMID34835153
PMCPMC8620087
OpenAlexW3206892081

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.