Evidence map›Paper›PMID 34835119›Full record

ArticleViruses2021

Persistence of SARS-CoV-2-Specific Antibodies for 13 Months after Infection.

Indrė Kučinskaitė-Kodzė, Martynas Simanavičius, Aistis Šimaitis, Aurelija Žvirblienė

Abstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Decoding the cross-immune pressure: Dengue's role in SARS-CoV-2 evolution.Computational and structural biotechnology journal · 2025
    Article
  3. Article
  4. Article
  5. Seroprevalence of Anti-SARS-CoV-2 Antibodies Following the Omicron BA.1 Wave.International journal of environmental research and public health · 2023
    Article
  6. SARS-CoV-2 antibodies persist up to 12 months after natural infection in healthy employees working in non-medical contact-intensive professions.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2023
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Indrė Kučinskaitė-KodzėLife Sciences Center, Vilnius University, Saulėtekio 7, LT-10257 Vilnius, Lithuania.ORCID 0000-0002-1761-0089
Martynas SimanavičiusLife Sciences Center, Vilnius University, Saulėtekio 7, LT-10257 Vilnius, Lithuania.ORCID 0000-0003-2996-229X
Aistis ŠimaitisThe Lithuanian Department of Statistics, Gedimino pr. 29, LT-01104 Vilnius, Lithuania.
Aurelija ŽvirblienėLife Sciences Center, Vilnius University, Saulėtekio 7, LT-10257 Vilnius, Lithuania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDynamics of antibody responses were investigated after a SARS-CoV-2 outbreak in a private company during the first wave of the pandemic.

methodsWorkers of a sewing company (Lithuania) with known SARS-CoV-2 RT-PCR result during the outbreak (April 2020) were invited to participate in the study. Virus-specific IgG and IgM were monitored 2, 6 and 13 months after the outbreak via rapid IgG/IgM serological test and SARS-CoV-2 S protein-specific IgG ELISA.

resultsSix months after the outbreak, 95% (CI 86-99%) of 59 previously infected individuals had virus-specific antibodies irrespective of the severity of infection. One-third of seropositive individuals had virus-specific IgM along with IgG indicating that IgM may persist for 6 months. Serological testing 13 months after the outbreak included 47 recovered individuals that remained non-vaccinated despite a wide accessibility of COVID-19 vaccines. The seropositivity rate was 83% (CI 69-91%) excluding one case of confirmed asymptomatic reinfection in this group. Between months 6 and 13, IgG levels either declined or remained stable in 31 individual and increased in 7 individuals possibly indicating an exposure to SARS-CoV-2 during the second wave of the pandemic.

conclusionsDetectable levels of SARS-CoV-2-specific antibodies persist up to 13 months after infection for the majority of the cases.

Indexed as

AdolescentAdultAgedAntibodies, ViralCohort StudiesCOVID-19COVID-19 Nucleic Acid TestingCOVID-19 Serological TestingCOVID-19 VaccinesDisease OutbreaksEnzyme-Linked Immunosorbent AssayFemaleHumansImmunoglobulin GImmunoglobulin MLithuaniaAntibodies, ViralCOVID-19 VaccinesImmunoglobulin GImmunoglobulin MIgG/IgM dynamicslongitudinal studySARS-CoV-2serological monitoring

Identifiers

PMID34835119
PMCPMC8622371

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.