ArticleViruses2021
Full Viral Genome Sequencing and Phylogenomic Analysis of Feline Herpesvirus Type 1 (FHV-1) in Cheetahs (
Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 52 citations in OpenAlex.
- Exposure to Feline Viruses in European Wildcats (Viruses · 2026Article
- Development of a Closed One-Tube Colorimetric and Fluorescent LAMP Assay for the Rapid Detection of Feline Herpesvirus 1.Animals : an open access journal from MDPI · 2026Article
- Isolation of a Variant of the Felid Herpesvirus 1-Live Attenuated Vaccine Strain F2 from Unvaccinated Cats.Intervirology · 2026Article
- Preparation of Monoclonal Antibodies Against the gD Protein of Feline Herpesvirus Type-1 by mRNA Immunization.Veterinary sciences · 2025Article
- Alphaherpesvirus in Pets and Livestock.Microorganisms · 2025Review
- A novel feline herpesvirus vector subunit FCV VP1 and FPV VP2 vaccine protects cats against FHV-1 and FPV challenge and induces serum neutralizing antibody responses against FCV.Frontiers in immunology · 2025Article
- Isolation of the feline herpesvirus-1 modified live vaccine strain F2 from one of four cats with dendritic ulcers.Journal of feline medicine and surgery · 2025Article
- Identification, Genetic Characterization, and Pathogenicity of Three Feline Herpesvirus Type 1 Isolates from Domestic Cats in China.Veterinary sciences · 2024Article
- Novel Alpha-, Beta-, and Gammaherpesviruses in Neotropical Carnivores of Brazil.Transboundary and emerging diseases · 2024Article
- Phylogenomic assessment of 23 equid alphaherpesvirus 1 isolates obtained from USA-based equids.Virology journal · 2023Article
- Feline herpesvirus 1 (FHV-1) enters the cell by receptor-mediated endocytosis.Journal of virology · 2023Article
- Pathogenicity and immunogenicity of gI/gE/TK-gene-deleted Felid herpesvirus 1 variants in cats.Virology journal · 2023Article
- Surveillance for feline herpesvirus type 1 mutation and development of resistance in cats treated with antiviral medications.Frontiers in veterinary science · 2023Article
- A Retrospective Study of Viral Molecular Prevalences in Cats in Southern Italy (Campania Region).Viruses · 2022Article
- Cross-species transmission of feline herpesvirus 1 (FHV-1) to chinchillas.Veterinary medicine and science · 2022Article
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Feline herpesvirus type 1 (FHV-1) is endemic in captive cheetahs and sporadically causes devastating disease. Modified live vaccines (MLV), intended for use in domestic cats, are used in some captive cheetah populations and have been anecdotally linked to disease in certain subpopulations. Ten FHV-1 isolates from ten captive cheetahs and one isolate from an MLV used to inoculate four of the host animals were analyzed. Viral DNA was extracted for full-genome sequencing by Illumina MiSeq with viral genomes then used for phylogenomic and recombinational analyses. The FHV-1 shed by vaccinated cheetahs were almost identical to the MLV, with few variants among viral genomes. Eight cheetah FHV-1 isolates and the MLV were grouped in a clade along with FHV-1 isolates from domestic cats in the USA. The remaining two cheetah FHV-1 isolates (unknown host vaccine status) were not associated with a clade. The likely ancestral origin of these two isolates involves recombination events between Australian domestic cat and cheetah FHV-1 isolates. Collectively, these data suggest that the MLV is capable of causing clinical disease and viral shedding in some cheetahs and represents evidence of interspecies transmission of virus between domestic and wild cats.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.