Evidence map›Paper›PMID 34835045›Full record

ArticleViruses2021

Lasting Changes to Circulating Leukocytes in People with Mild SARS-CoV-2 Infections.

Allison E Kennedy, Laura Cook, Jessica A Breznik, Braeden Cowbrough, Jessica G Wallace, Angela Huynh, James W Smith, Kiho Son, Hannah Stacey, Jann Ang and 14 more

Open access · goldAbstract readComparative Study
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 29 citations in OpenAlex.

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  12. Herpes zoster infection in pregnancy: features and consequences.Archives of dermatological research · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 4 institutions in 2 countries.

Allison E KennedyMcMaster Immunology Research Centre, McMaster University, Hamilton, ON L8S 4K1, Canada.ORCID 0000-0002-0247-0626
Laura CookBC Children's Hospital Research Institute, University of British Columbia, Vancouver, BC V5Z 4H4, Canada.ORCID 0000-0003-3153-2045
Jessica A BreznikMcMaster Immunology Research Centre, McMaster University, Hamilton, ON L8S 4K1, Canada.ORCID 0000-0002-5434-9158
Braeden CowbroughMcMaster Immunology Research Centre, McMaster University, Hamilton, ON L8S 4K1, Canada.
Jessica G WallaceMcMaster Immunology Research Centre, McMaster University, Hamilton, ON L8S 4K1, Canada.
Angela HuynhDepartment of Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, ON L8S 4K1, Canada.
James W SmithDepartment of Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, ON L8S 4K1, Canada.
Kiho SonDepartment of Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, ON L8S 4K1, Canada.ORCID 0000-0001-9478-1191
Hannah StaceyMcMaster Immunology Research Centre, McMaster University, Hamilton, ON L8S 4K1, Canada.
Jann AngMcMaster Immunology Research Centre, McMaster University, Hamilton, ON L8S 4K1, Canada.
Allison McGeerDepartment of Microbiology, Sinai Health, Toronto, ON M5G 1X5, Canada.
Brenda L ColemanDepartment of Microbiology, Sinai Health, Toronto, ON M5G 1X5, Canada.ORCID 0000-0002-7144-4827
Maggie LarchéDepartment of Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, ON L8S 4K1, Canada.
Mark LarchéDepartment of Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, ON L8S 4K1, Canada.
Nathan HamblyDepartment of Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, ON L8S 4K1, Canada.
Parameswaran NairDepartment of Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, ON L8S 4K1, Canada.
Kjetil AskDepartment of Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, ON L8S 4K1, Canada.
Matthew S MillerMcMaster Immunology Research Centre, McMaster University, Hamilton, ON L8S 4K1, Canada.ORCID 0000-0003-3426-5069
Jonathan BramsonMcMaster Immunology Research Centre, McMaster University, Hamilton, ON L8S 4K1, Canada.
Megan K LevingsBC Children's Hospital Research Institute, University of British Columbia, Vancouver, BC V5Z 4H4, Canada.
Ishac NazyDepartment of Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, ON L8S 4K1, Canada.
Sarah SvenningsenDepartment of Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, ON L8S 4K1, Canada.
Manali MukherjeeDepartment of Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, ON L8S 4K1, Canada.
Dawn M E BowdishMcMaster Immunology Research Centre, McMaster University, Hamilton, ON L8S 4K1, Canada.
McMaster University · CAInstitute for Respiratory Health · AUUniversity of British Columbia · CAUniversity of Toronto · CA

Funding

CIHR FDN-154304Ontario Research Fund (ORF) COVID-19 Rapid Research Fund #C-191-2426729-NAZYW. Garfield Weston Family Foundation NA
6 · The paper itself

Abstract

Survivors of severe SARS-CoV-2 infections frequently suffer from a range of post-infection sequelae. Whether survivors of mild or asymptomatic infections can expect any long-term health consequences is not yet known. Herein we investigated lasting changes to soluble inflammatory factors and cellular immune phenotype and function in individuals who had recovered from mild SARS-CoV-2 infections (

Indexed as

Asymptomatic InfectionsAdultAgedAntibodies, ViralBiomarkersCOVID-19C-Reactive ProteinCytokinesFemaleHumansImmunophenotypingInflammationLeukocytesLymphocyte ActivationMaleMiddle AgedAntibodies, ViralBiomarkersC-Reactive ProteinCytokinesSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2COVID-19immune activationimmunophenotypeinflammationSARS-CoV-2

Identifiers

PMID34835045
PMCPMC8622816
OpenAlexW3212635003

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.