Evidence map›Paper›PMID 34835034›Full record

ArticleViruses2021

Curing Cats with Feline Infectious Peritonitis with an Oral Multi-Component Drug Containing GS-441524.

Daniela Krentz, Katharina Zenger, Martin Alberer, Sandra Felten, Michèle Bergmann, Roswitha Dorsch, Kaspar Matiasek, Laura Kolberg, Regina Hofmann-Lehmann, Marina L Meli and 10 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 1 pooled it
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 1 synthesis or guideline pooled it, 81 citations in OpenAlex.

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4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 6 institutions in 3 countries.

Daniela KrentzClinic of Small Animal Medicine, Centre for Clinical Veterinary Medicine, LMU Munich, 80539 Munich, Germany.ORCID 0000-0002-6175-1153
Katharina ZengerClinic of Small Animal Medicine, Centre for Clinical Veterinary Medicine, LMU Munich, 80539 Munich, Germany.
Martin AlbererDivision of Paediatric Infectious Diseases, Dr. von Hauner Children's Hospital, University Hospital, LMU Munich, 80337 Munich, Germany.
Sandra FeltenClinic of Small Animal Medicine, Centre for Clinical Veterinary Medicine, LMU Munich, 80539 Munich, Germany.
Michèle BergmannClinic of Small Animal Medicine, Centre for Clinical Veterinary Medicine, LMU Munich, 80539 Munich, Germany.
Roswitha DorschClinic of Small Animal Medicine, Centre for Clinical Veterinary Medicine, LMU Munich, 80539 Munich, Germany.ORCID 0000-0002-7508-5411
Kaspar MatiasekSection of Clinical and Comparative Neuropathology, Institute of Veterinary Pathology, Centre for Clinical Veterinary Medicine, LMU Munich, 80539 Munich, Germany.
Laura KolbergDivision of Paediatric Infectious Diseases, Dr. von Hauner Children's Hospital, University Hospital, LMU Munich, 80337 Munich, Germany.ORCID 0000-0002-3311-8254
Regina Hofmann-LehmannClinical Laboratory, Department of Clinical Diagnostics and Services, and Center for Clinical Studies, Vetsuisse Faculty, University of Zurich, CH-8057 Zurich, Switzerland.ORCID 0000-0001-9750-4296
Marina L MeliClinical Laboratory, Department of Clinical Diagnostics and Services, and Center for Clinical Studies, Vetsuisse Faculty, University of Zurich, CH-8057 Zurich, Switzerland.ORCID 0000-0002-3609-2416
Andrea M SpiriClinical Laboratory, Department of Clinical Diagnostics and Services, and Center for Clinical Studies, Vetsuisse Faculty, University of Zurich, CH-8057 Zurich, Switzerland.ORCID 0000-0001-9009-8256
Jeannie HorakDepartment Paediatrics, Division Metabolic and Nutritional Medicine, Dr. von Hauner Children's Hospital, University Hospital, LMU Munich, 80337 Munich, Germany.
Saskia WeberInstitute of Novel and Emerging Infectious Diseases, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, 17493 Greifswald, Germany.ORCID 0000-0002-1492-7566
Cora M HolickiInstitute of Novel and Emerging Infectious Diseases, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, 17493 Greifswald, Germany.ORCID 0000-0002-1258-5646
Martin H GroschupInstitute of Novel and Emerging Infectious Diseases, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, 17493 Greifswald, Germany.ORCID 0000-0003-0215-185X
Yury ZablotskiClinic of Small Animal Medicine, Centre for Clinical Veterinary Medicine, LMU Munich, 80539 Munich, Germany.ORCID 0000-0001-6928-4089
Eveline LescrinierMedicinal Chemistry, KU Leuven, Rega Institute for Medical Research, 3000 Leuven, Belgium.ORCID 0000-0001-7066-4329
Berthold KoletzkoDepartment Paediatrics, Division Metabolic and Nutritional Medicine, Dr. von Hauner Children's Hospital, University Hospital, LMU Munich, 80337 Munich, Germany.ORCID 0000-0002-5345-7165
Ulrich von BothDivision of Paediatric Infectious Diseases, Dr. von Hauner Children's Hospital, University Hospital, LMU Munich, 80337 Munich, Germany.ORCID 0000-0001-8411-1071
Katrin HartmannClinic of Small Animal Medicine, Centre for Clinical Veterinary Medicine, LMU Munich, 80539 Munich, Germany.ORCID 0000-0002-5256-863X
Ludwig-Maximilians-Universität München · DEFriedrich-Loeffler-Institut · DEUniversity of Zurich · CHLMU Klinikum · DEGerman Center for Infection Research · DERega Institute for Medical Research · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Feline infectious peritonitis (FIP) caused by feline coronavirus (FCoV) is a common dis-ease in cats, fatal if untreated, and no effective treatment is currently legally available. The aim of this study was to evaluate efficacy and toxicity of the multi-component drug Xraphconn

Indexed as

AdenosineAnimalsAntibodies, ViralAntiviral AgentsCatsCell LineCoronavirus, FelineCoronavirus InfectionsFeline Infectious PeritonitisFemaleFollow-Up StudiesMaleProspective StudiesRNA, ViralSurvival RateViral LoadAdenosineAntibodies, ViralAntiviral AgentsGS-441524RNA, Viralantiviral chemotherapyFCoVfeline coronavirusFIPGS-441524MutiantherapytreatmentXraphconn®

Identifiers

PMID34835034
PMCPMC8621566
OpenAlexW3212168802

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.