Evidence map›Paper›PMID 34835031›Full record

ArticleViruses2021

Rapid Response to SARS-CoV-2 in Aotearoa New Zealand: Implementation of a Diagnostic Test and Characterization of the First COVID-19 Cases in the South Island.

Blair Lawley, Jenny Grant, Rhodri Harfoot, Jackson M Treece, Robert Day, Leonor C Hernández, Jo-Ann L Stanton, James E Ussher, Miguel E Quiñones-Mateu

Abstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Synthetic host defense peptide inhibits SARS-CoV-2 replicationAntimicrobial agents and chemotherapy · 2025
    Article
  2. Observational
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Blair LawleyDepartment of Microbiology & Immunology, School of Biomedical Sciences, University of Otago, 9054 Dunedin, New Zealand.
Jenny GrantSouthern Community Laboratories, Dunedin Hospital, 9054 Dunedin, New Zealand.
Rhodri HarfootDepartment of Microbiology & Immunology, School of Biomedical Sciences, University of Otago, 9054 Dunedin, New Zealand.
Jackson M TreeceDepartment of Anatomy, School of Biomedical Sciences, University of Otago, 9054 Dunedin, New Zealand.ORCID 0000-0003-1152-7214
Robert DayDepartment of Biochemistry, School of Biomedical Sciences, University of Otago, 9054 Dunedin, New Zealand.
Leonor C HernándezDepartment of Microbiology & Immunology, School of Biomedical Sciences, University of Otago, 9054 Dunedin, New Zealand.
Jo-Ann L StantonDepartment of Anatomy, School of Biomedical Sciences, University of Otago, 9054 Dunedin, New Zealand.ORCID 0000-0001-8139-4694
James E UssherDepartment of Microbiology & Immunology, School of Biomedical Sciences, University of Otago, 9054 Dunedin, New Zealand.ORCID 0000-0001-9222-7680
Miguel E Quiñones-MateuDepartment of Microbiology & Immunology, School of Biomedical Sciences, University of Otago, 9054 Dunedin, New Zealand.ORCID 0000-0001-9170-5601

Funding

Webster Family Chair in Viral Pathogenesis MQM
6 · The paper itself

Abstract

It has been 20 months since we first heard of SARS-CoV-2, the novel coronavirus detected in the Hubei province, China, in December 2019, responsible for the ongoing COVID-19 pandemic. Since then, a myriad of studies aimed at understanding and controlling SARS-CoV-2 have been published at a pace that has outshined the original effort to combat HIV during the beginning of the AIDS epidemic. This massive response started by developing strategies to not only diagnose individual SARS-CoV-2 infections but to monitor the transmission, evolution, and global spread of this new virus. We currently have hundreds of commercial diagnostic tests; however, that was not the case in early 2020, when just a handful of protocols were available, and few whole-genome SARS-CoV-2 sequences had been described. It was mid-January 2020 when several District Health Boards across New Zealand started planning the implementation of diagnostic testing for this emerging virus. Here, we describe our experience implementing a molecular test to detect SARS-CoV-2 infection, adapting the RT-qPCR assay to be used in a random-access platform (Hologic Panther Fusion

Indexed as

COVID-19 Nucleic Acid TestingSARS-CoV-2COVID-19FemaleGenome, ViralHumansMaleNew ZealandPhylogenyReproducibility of ResultsWhole Genome SequencingCOVID-19diagnostic testNew ZealandSARS-CoV-2whole-genome sequencing

Identifiers

PMID34835031
PMCPMC8623489

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.