Evidence map›Paper›PMID 34835008›Full record

ArticleViruses2021

Peritoneal Administration of a Subunit Vaccine Encapsulated in a Nanodelivery System Not Only Augments Systemic Responses against SARS-CoV-2 but Also Stimulates Responses in the Respiratory Tract.

Tuksin Jearanaiwitayakul, Suttikarn Apichirapokey, Runglawan Chawengkirttikul, Jitra Limthongkul, Mathurin Seesen, Phissinee Jakaew, Sakalin Trisiriwanich, Sompong Sapsutthipas, Panya Sunintaboon, Sukathida Ubol

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

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  9. T cells in SARS-CoV-2 infection and vaccination.Therapeutic advances in vaccines and immunotherapy · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Tuksin JearanaiwitayakulDepartment of Microbiology, Faculty of Science, Mahidol University, Bangkok 10400, Thailand.ORCID 0000-0002-2555-8516
Suttikarn ApichirapokeyDepartment of Microbiology, Faculty of Science, Mahidol University, Bangkok 10400, Thailand.
Runglawan ChawengkirttikulDepartment of Microbiology, Faculty of Science, Mahidol University, Bangkok 10400, Thailand.
Jitra LimthongkulDepartment of Microbiology, Faculty of Science, Mahidol University, Bangkok 10400, Thailand.
Mathurin SeesenDepartment of Microbiology, Faculty of Science, Mahidol University, Bangkok 10400, Thailand.
Phissinee JakaewDepartment of Microbiology, Faculty of Science, Mahidol University, Bangkok 10400, Thailand.
Sakalin TrisiriwanichInstitute of Biological Products, Department of Medical Sciences, Ministry of Public Health, Nonthaburi 11000, Thailand.
Sompong SapsutthipasInstitute of Biological Products, Department of Medical Sciences, Ministry of Public Health, Nonthaburi 11000, Thailand.
Panya SunintaboonDepartment of Chemistry, Faculty of Science, Mahidol University, Salaya, Nakornpatom 73170, Thailand.
Sukathida UbolDepartment of Microbiology, Faculty of Science, Mahidol University, Bangkok 10400, Thailand.
Mahidol University · THMinistry of Public Health · TH

Funding

National Vaccine Institute, Thailand 2563.1/9
6 · The paper itself

Abstract

The COVID-19 pandemic has currently created an unprecedented threat to human society and global health. A rapid mass vaccination to create herd immunity against SARS-CoV-2 is a crucial measure to ease the spread of this disease. Here, we investigated the immunogenicity of a SARS-CoV-2 subunit vaccine candidate, a SARS-CoV-2 spike glycoprotein encapsulated in

Indexed as

ImmunityAnimalsAntibodies, NeutralizingAntibodies, ViralAntibody FormationCOVID-19COVID-19 VaccinesFemaleHumansImmunity, MucosalImmunizationImmunogenicity, VaccineMiceMice, Inbred BALB CNanoparticle Drug Delivery SystemNanoparticlesAntibodies, NeutralizingAntibodies, ViralCOVID-19 VaccinesNanoparticle Drug Delivery SystemRecombinant ProteinsSpike Glycoprotein, Coronavirusspike glycoprotein, SARS-CoVVaccines, Subunitadjuvant delivery particlesCOVID-19 vaccinemucosal immunityperitoneal immunizationSARS-CoV-2 spike glycoprotein

Identifiers

PMID34835008
PMCPMC8617950
OpenAlexW3208758937

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.