Evidence map›Paper›PMID 34834999›Full record

ArticleViruses2021

Viral Phrenology.

David P Wilson, Danielle A Roof

Abstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

David P WilsonDepartment of Physics, Kalamazoo College, Kalamazoo, MI 49006, USA.ORCID 0000-0001-6637-3908
Danielle A RoofDepartment of Physics, Kalamazoo College, Kalamazoo, MI 49006, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We introduce Viral Phrenology, a new scheme for understanding the genomic composition of spherical viruses based on the locations of their structural protrusions. We used icosahedral point arrays to classify 135 distinct viral capsids collected from over 600 capsids available in the VIPERdb. Using gauge points of point arrays, we found 149 unique structural protrusions. We then show how to use the locations of these protrusions to determine the genetic composition of the virus. We then show that ssDNA, dsDNA, dsRNA and ssRNA viruses use different arrangements for distributing their protrusions. We also found that Triangulation number is also partially dependent on the structural protrusions. This analysis begins to tie together Baltimore Classification and Triangulation number using point arrays.

Indexed as

PhrenologyCapsidCryoelectron MicroscopyCrystallography, X-RayDNA, Single-StrandedGenome, ViralModels, MolecularNanomedicineNorovirusParvoviridaeRNA, Double-StrandedVirionVirusesDNA, Single-StrandedRNA, Double-StrandedBaltimore Classificationnanomedicinepoint arraysprotruding featuresspherical virussurface modificationsTriangulation numbervirus genomevirus-like particleVLP

Identifiers

PMID34834999
PMCPMC8618131

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.