Evidence map›Paper›PMID 34834943›Full record

ArticleViruses2021

Identification and Genetic Characterization of Viral Pathogens in Ruminant Gestation Abnormalities, Israel, 2015-2019.

Natalia Golender, Velizar Bumbarov, Anita Kovtunenko, Dan David, Marisol Guini-Rubinstein, Asaf Sol, Martin Beer, Avi Eldar, Kerstin Wernike

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
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  5. Research progress on the N gene of Akabane virus.Frontiers in veterinary science · 2025
    Review
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  7. Review
  8. Complete Thoracic Ectopia Cordis in Two Lambs.Animals : an open access journal from MDPI · 2024
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Natalia GolenderDepartment of Virology, Kimron Veterinary Institute, Bet Dagan 50250, Israel.ORCID 0000-0002-9074-7989
Velizar BumbarovDepartment of Virology, Kimron Veterinary Institute, Bet Dagan 50250, Israel.
Anita KovtunenkoDepartment of Virology, Kimron Veterinary Institute, Bet Dagan 50250, Israel.
Dan DavidDepartment of Virology, Kimron Veterinary Institute, Bet Dagan 50250, Israel.
Marisol Guini-RubinsteinDepartment of Virology, Kimron Veterinary Institute, Bet Dagan 50250, Israel.
Asaf SolDepartment of Virology, Kimron Veterinary Institute, Bet Dagan 50250, Israel.ORCID 0000-0002-8731-2490
Martin BeerInstitute of Diagnostic Virology, Friedrich-Loeffler-Institut, 17493 Greifswald-Insel Riems, Germany.
Avi EldarDepartment of Virology, Kimron Veterinary Institute, Bet Dagan 50250, Israel.
Kerstin WernikeInstitute of Diagnostic Virology, Friedrich-Loeffler-Institut, 17493 Greifswald-Insel Riems, Germany.ORCID 0000-0001-8071-0827
Ministry of Agriculture and Rural Development · ILFriedrich-Loeffler-Institut · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infectious agents including viruses are important abortifacients and can cause fetal abnormalities in livestock animals. Here, samples that had been collected in Israel from aborted or malformed ruminant fetuses between 2015 and 2019 were investigated for the presence of the following viruses: the reoviruses bluetongue virus (BTV) and epizootic hemorrhagic disease virus (EHDV), the flaviviruses bovine viral diarrhea virus (BVDV) and border disease virus (BDV), the peribunyaviruses Shuni virus (SHUV) and Akabane virus (AKAV), bovine herpesvirus type 1 (BoHV-1) and bovine ephemeral fever virus (BEFV). Domestic (cattle, sheep, goat) and wild/zoo ruminants were included in the study. The presence of viral nucleic acid or antigen could be confirmed in 21.8 % of abnormal pregnancies (213 out of 976 investigated cases), with peribunyaviruses, reoviruses and pestiviruses being the most prevalent. At least four different BTV serotypes were involved in abnormal courses of pregnancy in Israel. The subtyping of pestiviruses revealed the presence of two BDV and several distinct BVDV type 1 strains. The peribunyaviruses AKAV and SHUV were identified annually throughout the study period, however, variation in the extent of virus circulation could be observed between the years. In 2018, AKAV even represented the most detected pathogen in cases of small domestic ruminant gestation abnormalities. In conclusion, it was shown that various viruses are involved in abnormal courses of pregnancy in ruminants in Israel.

Indexed as

AnimalsBluetongue virusBorder disease virusCattleDiarrhea Virus 1, Bovine ViralDiarrhea Viruses, Bovine ViralFemaleGoat DiseasesGoatsHemorrhagic Disease Virus, EpizooticIsraelLivestockPestivirusPhylogenyPregnancyRuminantsabortionbunyaviruscattlefetal infectiongoatmalformationorbiviruspestivirussheep

Identifiers

PMID34834943
PMCPMC8619439
OpenAlexW3209580199

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.