Evidence map›Paper›PMID 34834564›Full record

ArticleJournal of personalized medicine2021

Fuyi Xu, Jun Gao, Buyan-Ochir Orgil, Akhilesh Kumar Bajpai, Qingqing Gu, Enkhsaikhan Purevjav, Athena S Davenport, Kui Li, Jeffrey A Towbin, Dennis D Black and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Fuyi XuSchool of Pharmacy, Binzhou Medical University, Yantai 264003, China.ORCID 0000-0002-5952-5771
Jun GaoDepartment of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, TN 38163, USA.ORCID 0000-0002-2372-4445
Buyan-Ochir OrgilDepartment of Pediatrics, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
Akhilesh Kumar BajpaiDepartment of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
Qingqing GuDepartment of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
Enkhsaikhan PurevjavDepartment of Pediatrics, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
Athena S DavenportDepartment of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, TN 38163, USA.ORCID 0000-0002-8938-237X
Kui LiDepartment of Microbiology, Immunology, and Biochemistry, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
Jeffrey A TowbinDepartment of Pediatrics, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
Dennis D BlackDepartment of Pediatrics, University of Tennessee Health Science Center, Memphis, TN 38163, USA.ORCID 0000-0002-1882-4310
Joseph F PierreDepartment of Pediatrics, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
Lu LuDepartment of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
University of Tennessee Health Science Center · USBinzhou Medical University · CNSt. Jude Children's Research Hospital · US

Funding

Discovery of modifier genes in cardiomyopathyR01HL151438 · NHLBI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI LU, LU, PUREVJAV, ENKHSAIKHAN · 2020 to 2023
$2.5M
Genetic and Environmental Determinants of GPRC6A Regulation of Energy Metabolism Using Genetically Engineered Mice and Systems BiologyR01DK120567 · NIDDK · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI LU, LU, PI, MIN · 2020 to 2023
$2.0M
NHLBI NIH HHS R01 HL151438NIH HHS R01DK120567Prevention and Control Research Incubation Program from Binzhou Medical University 50012305190
6 · The paper itself

Abstract

Studies showed that the gastrointestinal (GI) tract is one of the most important pathways for SARS-CoV-2 infection and coronavirus disease 2019 (COVID-19). As SARS-CoV-2 cellular entry depends on the ACE2 receptor and TMPRSS2 priming of the spike protein, it is important to understand the molecular mechanisms through which these two proteins and their cognate transcripts interact and influence the pathogenesis of COVID-19. In this study, we quantified the expression, associations, genetic modulators, and molecular pathways for

Indexed as

BXD miceco-expressionCOVID-19gastrointestinal tractmicrobiotaSARS-CoV-2systems geneticstranscriptome

Identifiers

PMID34834564
PMCPMC8621576
OpenAlexW3213532536

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.