ReviewJournal of personalized medicine2021
Sleep Dysfunction in COVID-19 Patients: Prevalence, Risk Factors, Mechanisms, and Management.
Review in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.
- Sleep disturbance increases the risk of severity and acquisition of COVID-19: a systematic review and meta-analysis.European journal of medical research · 2023Pooled it
- COVID-19 infection and sleep health: findings from the nationally representative COVID-19's Unequal Racial Burden survey.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025Article
- Parallel mediating effects of anxiety and depression on the relationship between sleep quality and fear of progression in individuals recovering from COVID-19.Frontiers in psychology · 2025Article
- Characteristics and Associated Factors of Insomnia Among the General Population in the Post-Pandemic Era of COVID-19 in Zhejiang, China: A Cross-Sectional Study.International journal of general medicine · 2025Article
- Insomnia during the COVID-19 pandemic: prevalence and correlates in a multi-ethnic population Singapore.BMC public health · 2024Article
- Alterations in Circadian Rhythms, Sleep, and Physical Activity in COVID-19: Mechanisms, Interventions, and Lessons for the Future.Molecular neurobiology · 2024Review
- Quality of Sleep and Mental Symptoms Contribute to Health-Related Quality of Life after COVID-19 Pneumonia, a Follow-Up Study of More than 2 Years.Biomedicines · 2024Article
- Management of long-COVID-19 patients with sleep disorders: practical advice to general practitioners.The Libyan journal of medicine · 2023Article
- Analysis of the relationship between sleep-related disorder and systemic immune-inflammation index in the US population.BMC psychiatry · 2023Article
- Fatigue in Post-Acute Sequelae of Coronavirus Disease 2019.Physical medicine and rehabilitation clinics of North America · 2023Review
- COVID-19 and Sleep Disturbances: A Literature Review of Clinical Evidence.Medicina (Kaunas, Lithuania) · 2023Review
- Neuropsychiatric aspects of long COVID: A comprehensive review.Psychiatry and clinical neurosciences · 2023Review
- Do selected lifestyle parameters affect the severity and symptoms of COVID-19 among elderly patients? The retrospective evaluation of individuals from the STOP-COVID registry of the PoLoCOV study.Journal of infection and public health · 2023Article
- Sleep Disturbance and Immunological Consequences of COVID-19.Patient preference and adherence · 2023Review
- Proper Dietary and Supplementation Patterns as a COVID-19 Protective Factor (Cross-Sectional Study-Silesia, Poland).Life (Basel, Switzerland) · 2022Article
- Persistent Sleep Quality Deterioration among Post-COVID-19 Patients: Results from a 6-Month Follow-Up Study.Journal of personalized medicine · 2022Article
- Sleep During the COVID-19 Pandemic.Current psychiatry reports · 2022Review
- Differences in the Course of Depression and Anxiety after COVID-19 Infection between Recovered Patients with and without a Psychiatric History: A Cross-Sectional Study.International journal of environmental research and public health · 2022Article
- Circadian misalignment is associated with Covid-19 infection.Sleep medicine · 2022Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
Abstract
During the COVID-19 pandemic, the need to establish the prevalence of sleep dysfunction and psychological distress, identify predisposing and protective factors, and explore effective management strategies remains an important priority. Evidence to date suggests that a considerable proportion of COVID-19 patients experience significant sleep disturbances (estimated to afflict up to 50-75%) as well as psychological distress such as depression, anxiety, and traumatic stress. Duration of hospitalization, pre-existing mental health concerns, lower absolute lymphocyte count, and increased neutrophil-to-lymphocyte ratio have been all associated with a greater risk of sleep dysfunction in infected and hospitalized patients. Furthermore, in this review, we discuss the link between sleep deprivation, susceptibility to viral infections, and psychosocial wellbeing in relevance to COVID-19 and summarize the existing evidence regarding the presence and role of sleep apnea in infected individuals. Finally, we highlight the importance of suitable interventions in order to prevent and manage sleep dysfunction and avoid long-term physical and psychological implications. Future research should aim to provide high-quality information including in high risk, underserved, or difficult to reach populations and on the long-term consequences and effectiveness of applied interventions.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.