Evidence map›Paper›PMID 34834520›Full record

ArticleJournal of personalized medicine2021

Statistical Analysis of the Main Risk Factors of an Unfavorable Evolution in Gastroschisis.

Elena Ţarcă, Solange Tamara Roșu, Elena Cojocaru, Laura Trandafir, Alina Costina Luca, Valeriu Vasile Lupu, Ștefana Maria Moisă, Valentin Munteanu, Lăcrămioara Ionela Butnariu, Viorel Ţarcă

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Elena ŢarcăDepartment of Surgery II-Pediatric Surgery, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iaşi, Romania.ORCID 0000-0002-3018-8011
Solange Tamara RoșuDepartment of Nursing, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iaşi, Romania.
Elena CojocaruDepartment of Morphofunctional Sciences I-Pathology, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iaşi, Romania.ORCID 0000-0001-7859-840X
Laura TrandafirDepartment of Mother and Child Medicine-Pediatrics, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iaşi, Romania.
Alina Costina LucaDepartment of Mother and Child Medicine-Pediatrics, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iaşi, Romania.
Valeriu Vasile LupuDepartment of Mother and Child Medicine-Pediatrics, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iaşi, Romania.ORCID 0000-0003-2640-8795
Ștefana Maria MoisăDepartment of Mother and Child Medicine-Pediatrics, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iaşi, Romania.
Valentin MunteanuDepartment of Biomedical Sciences, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iaşi, Romania.
Lăcrămioara Ionela ButnariuDepartment of Mother and Child Medicine-Genetics, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iaşi, Romania.
Viorel ŢarcăCounty Statistics Department, 700115 Iaşi, Romania.
Grigore T. Popa University of Medicine and Pharmacy · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastroschisis is a congenital abdominal wall defect that presents an increasing occurrence at great cost for the health system. The aim of the study is to detect the main factors of an unfavorable evolution in the case of gastroschisis and to find the best predictors of death.

methodswe conducted a retrospective cohort study of neonates with gastroschisis treated in a tertiary pediatric center during the last 30 years; 159 patients were eligible for the study. Logistic regression was used to determine the risk of death, estimated based on independent variables previously validated by the chi-square test.

resultsif the birth weight is below normal, then we find an increased risk (4.908 times) of evolution to death. Similarly, the risk of death is 7.782 times higher in the case of developing abdominal compartment syndrome, about 3 times in the case of sepsis and 7.883 times in the case of bronchopneumonia. All four independent variables contributed 47.6% to the risk of death.

conclusionalthough in the past 30 years in our country we have seen transformational improvements in outcome of gastroschisis, survival rates increasing from 26% to 52%, some factors may still be ameliorated for a better outcome.

Indexed as

gastroschisismorbiditymortalityoutcome

Identifiers

PMID34834520
PMCPMC8619615
OpenAlexW3212730210

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.