Evidence map›Paper›PMID 34834506›Full record

ArticleJournal of personalized medicine2021

Metabolic Syndrome Increases the Risk of Kidney Stone Disease: A Cross-Sectional and Longitudinal Cohort Study.

Che-Wei Chang, Hung-Lung Ke, Jia-In Lee, Yung-Chin Lee, Jhen-Hao Jhan, Hsun-Shuan Wang, Jung-Tsung Shen, Yao-Hsuan Tsao, Shu-Pin Huang, Jiun-Hung Geng

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 2 pooled it
6.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 2 syntheses or guidelines pooled it, 70 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Che-Wei ChangDepartment of Urology, Kaohsiung Municipal Siaogang Hospital, Kaohsiung 812, Taiwan.ORCID 0000-0003-1206-4733
Hung-Lung KeDepartment of Urology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 80756, Taiwan.
Jia-In LeeDepartment of Psychiatry, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 80756, Taiwan.
Yung-Chin LeeDepartment of Urology, Kaohsiung Municipal Siaogang Hospital, Kaohsiung 812, Taiwan.
Jhen-Hao JhanDepartment of Urology, Kaohsiung Municipal Siaogang Hospital, Kaohsiung 812, Taiwan.ORCID 0000-0003-3239-0712
Hsun-Shuan WangDepartment of Urology, Kaohsiung Municipal Siaogang Hospital, Kaohsiung 812, Taiwan.
Jung-Tsung ShenDepartment of Urology, Kaohsiung Municipal Siaogang Hospital, Kaohsiung 812, Taiwan.
Yao-Hsuan TsaoDepartment of Urology, Kaohsiung Municipal Siaogang Hospital, Kaohsiung 812, Taiwan.
Shu-Pin HuangDepartment of Urology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 80756, Taiwan.ORCID 0000-0003-2968-6125
Jiun-Hung GengDepartment of Urology, Kaohsiung Municipal Siaogang Hospital, Kaohsiung 812, Taiwan.ORCID 0000-0003-0610-1278
Kaohsiung Medical University · TWKaohsiung Municipal Hsiao-Kang Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aimed to examine the association between metabolic syndrome and the risk of kidney stone development in a large-scale community-based cohort. A total of 121,579 participants enrolled in the Taiwan Biobank were analyzed. They were divided into two groups on the basis of presence of metabolic syndrome. The presence of kidney stone disease was defined by self-reported history of kidney stones. The mean age of participants was 50 years old, and self-reported kidney stones were observed in 3446 (10%) and 4292 (5%) participants with metabolic syndrome and without metabolic syndrome, respectively. Higher prevalence of kidney stone disease was found in participants with metabolic syndrome compared to those without metabolic syndrome (odds ratio (OR), 1.32; 95% confidence interval (95% CI), 1.25 to 1.39). In addition, the risk of incident kidney stone development was analyzed in a longitudinal cohort of 25,263 participants without kidney stones at baseline during a mean follow-up of 47 months. Multivariable Cox regression analysis revealed that the risk for incident kidney stone disease was higher in participants with metabolic syndrome than those without metabolic syndrome (hazard ratio, 1.24; 95% CI, 1.04 to 1.49). Our study suggests that metabolic syndrome does increase the risk of kidney stones.

Indexed as

diabetes mellitusdyslipidemiaepidemiologic studyhypertensionkidney stonelongitudinal studymetabolic syndromerisk factors

Identifiers

PMID34834506
PMCPMC8622125
OpenAlexW3212512524

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.