Evidence map›Paper›PMID 34834443›Full record

ArticleJournal of personalized medicine2021

The Effect of Bisphenol A on the IVF Outcomes Depending on the Polymorphism of the Detoxification System Genes.

Anastasiya Syrkasheva, Vladimir Frankevich, Svetlana Kindysheva, Nataliia Starodubtseva, Andrey Donnikov, Nataliya Dolgushina

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Anastasiya SyrkashevaV.I. Kulakov National Medical Research Center for Obstetrics, ART Department, Gynecology and Perinatology Ministry of Healthcare of Russian Federation, 4 Oparin Str., 117997 Moscow, Russia.ORCID 0000-0002-7150-2230
Vladimir FrankevichV.I. Kulakov National Medical Research Center for Obstetrics, Department of Systems Biology in Reproduction, Gynecology and Perinatology Ministry of Healthcare of Russian Federation, 4 Oparin Str., 117997 Moscow, Russia.
Svetlana KindyshevaV.I. Kulakov National Medical Research Center for Obstetrics, Department of Systems Biology in Reproduction, Gynecology and Perinatology Ministry of Healthcare of Russian Federation, 4 Oparin Str., 117997 Moscow, Russia.
Nataliia StarodubtsevaV.I. Kulakov National Medical Research Center for Obstetrics, Laboratory of Proteomics of Human Reproduction, Gynecology and Perinatology Ministry of Healthcare of Russian Federation, 4 Oparin Str., 117997 Moscow, Russia.
Andrey DonnikovV.I. Kulakov National Medical Research Center for Obstetrics, Department of Molecular Genetic Methods, Gynecology and Perinatology Ministry of Healthcare of Russian Federation, 4 Oparin Str., 117997 Moscow, Russia.
Nataliya DolgushinaV.I. Kulakov National Medical Research Center for Obstetrics, R&D Department, Gynecology and Perinatology Ministry of Healthcare of Russian Federation, 4 Oparin Str., 117997 Moscow, Russia.
National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I.Kulakov of the Ministry of Healthcare of the Russian Federation · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the study was to analyze the relationship between the level of bisphenol A (BPA) in the blood and follicular fluid, the polymorphism of the detoxification system genes, and the outcomes of IVF cycles. The data of 300 infertile patients with fresh IVF-ET cycles were analyzed. The level of BPA in the blood and follicular fluid was determined by HPLC-MRM-MS/MS. Determination of genotypes of the detoxification system genes was carried out by the real-time PCR. The threshold level for determining BPA was 0.1 ng/mL. BPA was detected in 92.3% (277/300) blood and in 16.8% (49/292) follicular fluid (FF) samples. There was no correlation between BPA level in the blood and FF. In patients with the absence of the A allele of the

Indexed as

assisted reproductive technologiesbisphenol Adetoxification genesembryoendocrine disruptorsgene polymorphism (SNP)HPLC-MSpregnancy

Identifiers

PMID34834443
PMCPMC8624790
OpenAlexW3209365868

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.