Evidence map›Paper›PMID 34834441›Full record

ArticleJournal of personalized medicine2021

Potential Prognostic Biomarkers of NIMA (Never in Mitosis, Gene A)-Related Kinase (NEK) Family Members in Breast Cancer.

Gangga Anuraga, Wei-Jan Wang, Nam Nhut Phan, Nu Thuy An Ton, Hoang Dang Khoa Ta, Fidelia Berenice Prayugo, Do Thi Minh Xuan, Su-Chi Ku, Yung-Fu Wu, Vivin Andriani and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed
9.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 93 citations in OpenAlex.

  1. Article
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  13. Review
  14. Mutational insights andFrontiers in bioinformatics · 2025
    Article
  15. Article
  16. Article
  17. Role of NEK2 in tumorigenesis and tumor progression.Trends in molecular medicine · 2025
    Review
  18. Epigenetics · 2024
    Article
  19. Article
  20. Article

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 3 countries.

Gangga AnuragaPhD Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University and Academia Sinica, Taipei 11031, Taiwan.ORCID 0000-0002-0902-3968
Wei-Jan WangResearch Center for Cancer Biology, Department of Biological Science and Technology, China Medical University, Taichung 40604, Taiwan.
Nam Nhut PhanInstitute for Environmental Science, Nguyen Tat Thanh University, Ho Chi Minh City 700000, Vietnam.
Nu Thuy An TonInstitute for Environmental Science, Nguyen Tat Thanh University, Ho Chi Minh City 700000, Vietnam.
Hoang Dang Khoa TaPhD Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University and Academia Sinica, Taipei 11031, Taiwan.ORCID 0000-0001-8809-239X
Fidelia Berenice PrayugoGraduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan.
Do Thi Minh XuanGraduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan.
Su-Chi KuGraduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan.ORCID 0000-0001-6832-9994
Yung-Fu WuDepartment of Medical Research, Tri-Service General Hospital, School of Medicine, National Defense Medical Center, Taipei 11490, Taiwan.
Vivin AndrianiDepartment of Biological Science, Faculty of Science and Technology, Universitas PGRI Adi Buana, Surabaya 60234, Indonesia.
Muhammad AthoillahDepartment of Statistics, Faculty of Science and Technology, Universitas PGRI Adi Buana, Surabaya 60234, Indonesia.ORCID 0000-0002-1800-1314
Kuen-Haur LeePhD Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University and Academia Sinica, Taipei 11031, Taiwan.ORCID 0000-0002-6354-3315
Chih-Yang WangPhD Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University and Academia Sinica, Taipei 11031, Taiwan.ORCID 0000-0002-4137-5074
Taipei Medical University · TWUniversitas PGRI Semarang · IDTrường ĐH Nguyễn Tất Thành · VNChina Medical University · TWTri-Service General Hospital · TWWan Fang Hospital · TW

Funding

Ministry of Science and Technology (MOST) of Taiwan MOST-110-2320-B-039-068
6 · The paper itself

Abstract

Breast cancer remains the most common malignant cancer in women, with a staggering incidence of two million cases annually worldwide; therefore, it is crucial to explore novel biomarkers to assess the diagnosis and prognosis of breast cancer patients. NIMA-related kinase (NEK) protein kinase contains 11 family members named NEK1-NEK11, which were discovered from

Indexed as

bioinformaticsbiomarkerbreast cancerfunctional enrichment analysisimmune infiltrationimmune microenvironmentNEK family genesprognosis

Identifiers

PMID34834441
PMCPMC8625415
OpenAlexW3210619064

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.