ArticlePharmaceutics2021
Manganese-Doped N-Hydroxyphthalimide-Derived Carbon Dots-Theranostics Applications in Experimental Breast Cancer Models.
Article in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Carbon Dots Meet MRI: Metal Doping for a Smart Contrast Agent Design.International journal of molecular sciences · 2026Review
- Antioxidant activity and in vitro fluorescence imaging application of N-, O- functionalized carbon dots.Scientific reports · 2025Article
- Mn-Doped Carbon Dots as Contrast Agents for Magnetic Resonance and Fluorescence Imaging.International journal of molecular sciences · 2025Article
- Enhancing Antioxidant and Cytotoxic Properties of CeONanomaterials (Basel, Switzerland) · 2025Article
- Surface-Modified Carbon Dots for Cancer Therapy: Integrating Diagnostic and Therapeutic Applications.International journal of nanomedicine · 2025Review
- Antibacterial and Antitumor Application of Carbon Dots Based on Natural Products for Photodynamic/Photothermal Effects.International journal of nanomedicine · 2025Article
- Nanotechnology-Driven Treatment Strategies for Breast Cancer: Recent Advances and Innovations.Oncology research · 2025Review
- 8-Anilino-1-naphthalenesulfonate-Conjugated Carbon-Coated Ferrite Nanodots for Fluoromagnetic Imaging, Smart Drug Delivery, and Biomolecular Sensing.Pharmaceutics · 2024Article
- Tumor diagnosis using carbon-based quantum dots: Detection based on the hallmarks of cancer.Bioactive materials · 2024Review
- Synthesis and evaluation of new magneto-fluorescent carbon dot based on manganese citrate for MRI imaging.Magma (New York, N.Y.) · 2024Article
- Photoluminescence of Argan-Waste-Derived Carbon Nanodots Embedded in Polymer Matrices.Nanomaterials (Basel, Switzerland) · 2023Article
- Metal-doped carbon dots as peroxidase mimic for hydrogen peroxide and glucose detection.Analytical and bioanalytical chemistry · 2022Article
- SI-ATRP Decoration of Magnetic Nanoparticles with PHEMA and Post-Polymerization Modification with Folic Acid for Tumor Cells' Specific Targeting.International journal of molecular sciences · 2021Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundTheranostics, a novel concept in medicine, is based on the use of an agent for simultaneous diagnosis and treatment. Nanomaterials provide promising novel approaches to theranostics. Carbon Dots have been shown to exhibit anti-tumoral properties in various cancer models. The aim of the present study is to develop gadolinium, Fe
methodsNormal and cancer cell lines have been treated with doped Carbon Dots, and the cell viability has been measured. The doped Carbon Dots that exhibited the most prominent anti-tumoral effect accompanied by the lowest toxicity have been further in vivo tested. Magnetic resonance imaging evaluates both in vitro and in vivo the possibility of using doped Carbon Dots as a contrast agent.
resultsAccording to the results obtained from both the in vitro and in vivo experimental models used in our study, Mn
conclusionsOur findings prove that Mn-CDs-NHF can be used as theranostics agents in pre-clinical models.
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