Evidence map›Paper›PMID 34834291›Full record

ReviewPharmaceutics2021

Chitosan-Based Biocompatible Copolymers for Thermoresponsive Drug Delivery Systems: On the Development of a Standardization System.

Lorenzo Marsili, Michele Dal Bo, Federico Berti, Giuseppe Toffoli

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
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  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lorenzo MarsiliDepartment of Chemical and Pharmaceutical Sciences, University of Trieste, Via Licio Giorgieri 1, 34127 Trieste, Italy.
Michele Dal BoExperimental and Clinical Pharmacology Unit, CRO National Cancer Institute IRCCS, Via Franco Gallini 2, 33081 Aviano, Italy.ORCID 0000-0001-8668-7621
Federico BertiDepartment of Chemical and Pharmaceutical Sciences, University of Trieste, Via Licio Giorgieri 1, 34127 Trieste, Italy.ORCID 0000-0001-5608-3798
Giuseppe ToffoliExperimental and Clinical Pharmacology Unit, CRO National Cancer Institute IRCCS, Via Franco Gallini 2, 33081 Aviano, Italy.ORCID 0000-0002-5323-4762

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chitosan is a natural polysaccharide that is considered to be biocompatible, biodegradable and non-toxic. The polymer has been used in drug delivery applications for its positive charge, which allows for adhesion with and recognition of biological tissues via non-covalent interactions. In recent times, chitosan has been used for the preparation of graft copolymers with thermoresponsive polymers such as poly-

Indexed as

chitosandrug deliverypoly-N-vinyl caprolactamreproducibilitysmart drug delivery systemsthermoresponsive polymers

Identifiers

PMID34834291
PMCPMC8620438

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.