Evidence map›Paper›PMID 34834290›Full record

ReviewPharmaceutics2021

Pharmaceutical Aspects of Nanocarriers for Smart Anticancer Therapy.

Seung Rim Hwang, Kushal Chakraborty, Jeong Man An, Jagannath Mondal, Hong Yeol Yoon, Yong-Kyu Lee

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Tableting of nanoparticle-based formulations for oral delivery: Enhancing biopharmaceutical performance.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2026
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  2. Navigating theNanoscale advances · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Seung Rim HwangCollege of Pharmacy, Chosun University, 309 Pilmun-daero, Dong-gu, Gwangju 61452, Korea.ORCID 0000-0002-3250-3396
Kushal ChakrabortyDepartment of IT and Energy Convergence (BK21 FOUR), Korea National University of Transportation, Chungju 27469, Korea.
Jeong Man AnDepartment of Bioengineering, College of Engineering, Hanyang University, Seoul 04763, Korea.
Jagannath MondalDepartment of Green Bio Engineering, Graduate School, Korea National University of Transportation, Chungju 27469, Korea.ORCID 0000-0001-9036-2635
Hong Yeol YoonCenter for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology (KIST), Seoul 02792, Korea.ORCID 0000-0003-3242-3633
Yong-Kyu LeeDepartment of IT and Energy Convergence (BK21 FOUR), Korea National University of Transportation, Chungju 27469, Korea.

Funding

Ministry of Environment YL-WE-19-002
6 · The paper itself

Abstract

Drug delivery to tumor sites using nanotechnology has been demonstrated to overcome the drawbacks of conventional anticancer drugs. Altering the surface shape and geometry of nanocomposites alters their chemical properties, which can confer multiple attributes to nanocarriers for the treatment of cancer and their use as imaging agents for cancer diagnosis. However, heterogeneity and blood flow in human cancer limit the distribution of nanoparticles at the site of tumor tisues. For targeted delivery and controlled release of drug molecules in harsh tumor microenvironments, smart nanocarriers combined with various stimuli-responsive materials have been developed. In this review, we describe nanomaterials for smart anticancer therapy as well as their pharmaceutical aspects including pharmaceutical process, formulation, controlled drug release, drug targetability, and pharmacokinetic or pharmacodynamic profiles of smart nanocarriers. Inorganic or organic-inorganic hybrid nanoplatforms and the electrospinning process have also been briefly described here.

Indexed as

cancerelectrospinninghybridinorganiclipidnanocarrierpharmaceuticalpolymersmartvirus

Identifiers

PMID34834290
PMCPMC8619450

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.