Evidence map›Paper›PMID 34834154›Full record

SynthesisMolecules (Basel, Switzerland)2021

Protease Produced by Endophytic Fungi: A Systematic Review.

Victor Hugo Souto Bezerra, Samuel Leite Cardoso, Yris Fonseca-Bazzo, Dâmaris Silveira, Pérola Oliveira Magalhães, Paula Monteiro Souza

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Secretion of serine proteases by planktonic- and biofilm-growing cells of Candida parapsilosis.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  3. Review
  4. Dynamic proteomic changes and ultrastructural insights intoFrontiers in cellular and infection microbiology · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. First Insight into the Degradome ofInternational journal of molecular sciences · 2024
    Article
  9. Review
  10. Bioprospecting ofFrontiers in microbiology · 2024
    Review
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Victor Hugo Souto BezerraNatural Products Laboratory, Campus Darcy Ribeiro, School of Health Sciences, University of Brasilia, Brasília 70910-900, DF, Brazil.
Samuel Leite CardosoNatural Products Laboratory, Campus Darcy Ribeiro, School of Health Sciences, University of Brasilia, Brasília 70910-900, DF, Brazil.
Yris Fonseca-BazzoNatural Products Laboratory, Campus Darcy Ribeiro, School of Health Sciences, University of Brasilia, Brasília 70910-900, DF, Brazil.ORCID 0000-0002-1230-3207
Dâmaris SilveiraNatural Products Laboratory, Campus Darcy Ribeiro, School of Health Sciences, University of Brasilia, Brasília 70910-900, DF, Brazil.ORCID 0000-0003-1851-5224
Pérola Oliveira MagalhãesNatural Products Laboratory, Campus Darcy Ribeiro, School of Health Sciences, University of Brasilia, Brasília 70910-900, DF, Brazil.ORCID 0000-0001-8011-6940
Paula Monteiro SouzaNatural Products Laboratory, Campus Darcy Ribeiro, School of Health Sciences, University of Brasilia, Brasília 70910-900, DF, Brazil.
Universidade de Brasília · BR

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior 0000Foundation for Research Support of the Federal District 193.001.528/2017
6 · The paper itself

Abstract

The purpose of this systematic review was to identify the available literature of production, purification, and characterization of proteases by endophytic fungi. There are few complete studies that entirely exhibit the production, characterization, and purification of proteases from endophytic fungi. This study followed the PRISMA, and the search was conducted on five databases: PubMed, PMC, Science Direct, Scopus Articles, and Web of Science up until 18 May 2021, with no time or language restrictions. The methodology of the selected studies was evaluated using GRADE. Protease production, optimization, purification, and characterization were the main evaluated outcomes. Of the 5540 initially gathered studies, 15 met the inclusion criteria after a two-step selection process. Only two studies optimized the protease production using statistical design and two reported enzyme purification and characterization. The genus

Indexed as

AspergillusEndophytesFungal ProteinsPenicilliumPeptide HydrolasesFungal ProteinsPeptide Hydrolasesendophytic fungiproteasesystematic review

Identifiers

PMID34834154
PMCPMC8623497
OpenAlexW3216866755

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.