Evidence map›Paper›PMID 34834151›Full record

ArticleMolecules (Basel, Switzerland)2021

Amidine- and Amidoxime-Substituted Heterocycles: Synthesis, Antiproliferative Evaluations and DNA Binding.

Silvija Maračić, Petra Grbčić, Suresh Shammugam, Marijana Radić Stojković, Krešimir Pavelić, Mirela Sedić, Sandra Kraljević Pavelić, Silvana Raić-Malić

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Silvija MaračićDepartment of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulićev trg 19, HR-10000 Zagreb, Croatia.ORCID 0000-0002-0896-3376
Petra GrbčićDepartment of Biotechnology, University of Rijeka, Ulica Radmile Matejčić 2, HR-51000 Rijeka, Croatia.ORCID 0000-0002-5711-6237
Suresh ShammugamDivision of Organic Chemistry and Biochemistry, Laboratory for Biomolecular Interactions and Spectroscopy, Ruđer Bošković Institute, Bijenička 54, HR-10000 Zagreb, Croatia.
Marijana Radić StojkovićDivision of Organic Chemistry and Biochemistry, Laboratory for Biomolecular Interactions and Spectroscopy, Ruđer Bošković Institute, Bijenička 54, HR-10000 Zagreb, Croatia.ORCID 0000-0003-4040-6534
Krešimir PavelićFaculty of Medicine, Juraj Dobrila University of Pula, HR-52100 Pula, Croatia.ORCID 0000-0001-7706-6858
Mirela SedićCentre for Applied Bioanthropology, Institute for Anthropological Research, Ljudevita Gaja 32, HR-10000 Zagreb, Croatia.ORCID 0000-0003-4679-1541
Sandra Kraljević PavelićFaculty of Health Studies, University of Rijeka, Ulica Viktora Cara Emina 5, HR-51000 Rijeka, Croatia.ORCID 0000-0003-0491-673X
Silvana Raić-MalićDepartment of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulićev trg 19, HR-10000 Zagreb, Croatia.ORCID 0000-0001-5021-8970
Ruđer Bošković Institute · HRUniversity of Rijeka · HRUniversity of Zagreb · HRInstitute for Anthropological Research · HRJuraj Dobrila University of Pula · HR

Funding

Croatian Science Foundation IP-2018-01-4682Croatian Science Foundation IP-2018-01-4694
6 · The paper itself

Abstract

The novel 1,2,3-triazolyl-appended

Indexed as

Cell ProliferationDNA, NeoplasmIntercalating AgentsNeoplasmsA549 CellsAntineoplastic AgentsHeLa CellsHep G2 CellsHumansOximesamidoximeAntineoplastic AgentsDNA, NeoplasmIntercalating AgentsOximesamidineamidoximeantiproliferative activityCD spectroscopyDNA bindingfluorescencethermal denaturation

Identifiers

PMID34834151
PMCPMC8625065
OpenAlexW3215779635

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.