Evidence map›Paper›PMID 34834146›Full record

ArticleMolecules (Basel, Switzerland)2021

Synthesis and Characterization of the Ethylene-Carbonate-Linked L-Valine Derivatives of 4,4-Dimethylcurcumin with Potential Anticancer Activities.

Der-Yen Lee, Hui-Yi Lin, Manickavasakam Ramasamy, Sheng-Chu Kuo, Pei-Chih Lee, Min-Tsang Hsieh

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Der-Yen LeeGraduate Institute of Integrated Medicine, China Medical University, No. 91, Hsueh-Shih Road, Taichung 40402, Taiwan.
Hui-Yi LinResearch Center for Chinese Herbal Medicine, China Medical University, Taichung 40402, Taiwan.
Manickavasakam RamasamySchool of Pharmacy, China Medical University, Taichung 40402, Taiwan.
Sheng-Chu KuoResearch Center for Chinese Herbal Medicine, China Medical University, Taichung 40402, Taiwan.
Pei-Chih LeeGraduate Institute of Biomedical Sciences, China Medical University, Taichung 40402, Taiwan.ORCID 0000-0002-7718-4069
Min-Tsang HsiehResearch Center for Chinese Herbal Medicine, China Medical University, Taichung 40402, Taiwan.ORCID 0000-0001-7287-9278
China Medical University · TW

Funding

China medical university CMU108-YTY-03China medical university CMU109-S-35Ministry of Education CMRC-CHM-5Ministry of Science and Technology 108-2320-B-039-036
6 · The paper itself

Abstract

Natural phenolic products from herbal medicines and dietary plants constitute the main source of lead compounds for the development of the new drug. 4,4-Dimethylcurcumin (

Indexed as

Antineoplastic AgentsCurcuminA549 CellsCell ProliferationHumansNeoplasmsAntineoplastic AgentsCurcumin4,4-dimethylcurcumincellular uptakeLC-MS spectroscopylung cancerwater solubility

Identifiers

PMID34834146
PMCPMC8624457
OpenAlexW3214830192

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.