Evidence map›Paper›PMID 34834077›Full record

ArticleMolecules (Basel, Switzerland)2021

Validation of the Developed Zero-Order Infrared Spectrophotometry Method for Qualitative and Quantitative Analyses of Tranexamic Acid in Marketed Tablets.

Nerdy Nerdy, Linda Margata, Bunga Mari Sembiring, Selamat Ginting, Effendy De Lux Putra, Tedy Kurniawan Bakri

Abstract readValidation Study
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nerdy NerdyDepartment of Pharmacy, Faculty of Pharmacy, Institut Kesehatan Deli Husada Deli Tua, Deli Tua Timur, Deli Tua, Deli Serdang 20355, Indonesia.ORCID 0000-0002-1993-4415
Linda MargataDepartment of Pharmacy, Faculty of Pharmacy, Institut Kesehatan Deli Husada Deli Tua, Deli Tua Timur, Deli Tua, Deli Serdang 20355, Indonesia.
Bunga Mari SembiringDepartment of Public Health, Faculty of Public Health, Institut Kesehatan Deli Husada Deli Tua, Deli Tua Timur, Deli Tua, Deli Serdang 20355, Indonesia.
Selamat GintingDepartment of Public Health, Faculty of Public Health, Institut Kesehatan Deli Husada Deli Tua, Deli Tua Timur, Deli Tua, Deli Serdang 20355, Indonesia.
Effendy De Lux PutraDepartment of Pharmacy, Faculty of Pharmacy, Universitas Sumatera Utara, Padang Bulan, Medan Baru, Medan 20155, Indonesia.
Tedy Kurniawan BakriDepartment of Pharmacy, Faculty of Mathematics and Natural Sciences, Universitas Syiah Kuala, Kopelma Darussalam, Syiah Kuala, Banda Aceh 23111, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: The functional groups present in tranexamic acid allow direct infrared detection analysis. This study aimed to develop, apply, and validate an infrared spectrophotometry method used for qualitative and quantitative analyses of tranexamic acid in marketed tablets. (2) Methods: This was a descriptive observational study that consisted of several stages: determining the specific wavenumber for analysis, obtaining a simple linear regression equation, analyzing tranexamic acid both qualitatively and quantitatively, and validating the developed method for routine analysis. (3) Results: The peak analysis obtained a range of baseline wavenumbers from 1679.17 to 1295.25 cm

Indexed as

Limit of DetectionReproducibility of ResultsSpectrophotometry, InfraredTabletsTranexamic AcidTabletsTranexamic Acidinfrared spectrophotometryqualitativequantitativetranexamic acidvalidation

Identifiers

PMID34834077
PMCPMC8618946

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.