ReviewMolecules (Basel, Switzerland)2021
A Focused Review of Synthetic Applications of Lawesson's Reagent in Organic Synthesis.
Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 34 citations in OpenAlex.
- High-TAngewandte Chemie (International ed. in English) · 2026Article
- Structure-Activity Relationship Study on Soticlestat Derivatives for the Discovery of CYP46A1 (CH24H) Inhibitors.Molecules (Basel, Switzerland) · 2026Article
- 5-Substituted 4-Thiouridines, 4-Thio-2'-deoxyuridines and Their Oligoglycol Carbonate Prodrugs as Promising Antimicrobial Agents.International journal of molecular sciences · 2025Article
- Effect of Chalcogen-Phosphorus Substituents on Enediynes Undergoing the Bergman Cyclization.Inorganic chemistry · 2025Article
- Synthesis of Dithioester Derivatives by Base-Mediated Fragmentation of 1,3-Dithiolanes.Organic letters · 2025Article
- Synthesis of Thionated Perylenediimides: State of the Art and First Investigations of an Alternative to Lawesson's Reagent.Molecules (Basel, Switzerland) · 2024Review
- Structure-Photoreactivity Relationship Study of Substituted 3-Hydroxyflavones and 3-Hydroxyflavothiones for Improving Carbon Monoxide Photorelease.The Journal of organic chemistry · 2024Article
- Thiocarbonyl Derivatives of Natural Chlorins: Synthesis Using Lawesson's Reagent and a Study of Their Properties.Molecules (Basel, Switzerland) · 2023Article
- A Terphenyl Supported Dioxophosphorane Dimer: the Light Congener of Lawesson's and Woollins' Reagents.Chemistry (Weinheim an der Bergstrasse, Germany) · 2022Article
- Recent advances in the transition-metal-free synthesis of quinoxalines.RSC advances · 2021Review
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Authors and funding
2 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Lawesson's reagent (LR) is a well-known classic example of a compound with unique construction and unusual chemical behavior, with a wide range of applications in synthetic organic chemistry. Its main functions were rounded for the thionation of various carbonyl groups in the early days, with exemplary results. However, the role of Lawesson's reagent in synthesis has changed drastically, and now its use can help the chemistry community to understand innovative ideas. These include constructing biologically valuable heterocycles, coupling reactions, and the thionation of natural compounds. The ease of availability and the convenient usage of LR as a thionating agent made us compile a review on the new diverse applications on some common functional groups, such as ketones, esters, amides, alcohols, and carboxylic acids, with biological applications. Since the applications of LR are now diverse, we have also included some new classes of heterocycles such as thiazepines, phosphine sulfides, thiophenes, and organothiophosphorus compounds. Thionation of some biologically essential steroids and terpenoids has also been compiled. This review discusses the recent insights into and synthetic applications of this famous reagent from 2009 to January 2021.
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