Characterization of Microbial Degradation Products of Steviol Glycosides.

Gert Steurs, Nico Moons, Luc Van Meervelt, Boudewijn Meesschaert, Wim Michel De Borggraeve

Abstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gert SteursDivision of Molecular Design and Synthesis, Department of Chemistry, KU Leuven, Celestijnenlaan 200f, P.O. Box 2404, 3001 Leuven, Belgium.ORCID 0000-0002-9779-7743

Nico MoonsDivision of Molecular Design and Synthesis, Department of Chemistry, KU Leuven, Celestijnenlaan 200f, P.O. Box 2404, 3001 Leuven, Belgium.

Luc Van MeerveltDivision of Biochemistry, Molecular and Structural Biology, Department of Chemistry, KU Leuven, Celestijnenlaan 200f, P.O. Box 2404, 3001 Leuven, Belgium.ORCID 0000-0003-2186-5209

Boudewijn MeesschaertLaboratory for Microbial and Biochemical Technology, Department of Microbial and Molecular Systems, KU Leuven Bruges Campus, Spoorwegstraat 12, P.O. Box 7913, 8200 Brugge, Belgium.

Wim Michel De BorggraeveDivision of Molecular Design and Synthesis, Department of Chemistry, KU Leuven, Celestijnenlaan 200f, P.O. Box 2404, 3001 Leuven, Belgium.ORCID 0000-0001-7813-6192

Funding

Herculesstichting 20100225-7Herculesstichting AKUL/09/0035Research Foundation - Flanders 1SC3121N.

6 · The paper itself

Abstract

Steviol glycosides were subjected to bacteria present in a soil sample collected from a Stevia plantation in Paraguay. During the incubation experiments, next to the aglycon steviol, steviol degradation products were also formed. X-ray analysis and NMR methods in combination with chemical synthesis and GIAO NMR calculations were used to fully characterize the structure of these compounds as a tricyclic ketone and the corresponding reduced form. They were nicknamed

Indexed as

Diterpenes, KauraneGlucosidesPlant LeavesSteviaDiterpenes, KauraneGlucosidessteviosideGIAO NMR calculationsmicrobial degradationmonicanolmonicanoneNMRsoil bacteriasteviol glycoside degradationX-ray structure

Identifiers

PMID34834008

DOI10.3390/molecules26226916

PMCPMC8625998

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.