Evidence map›Paper›PMID 34833990›Full record

ReviewMolecules (Basel, Switzerland)2021

Anti-Inflammatory and Antioxidant Properties of Carvacrol and Magnolol, in Periodontal Disease and Diabetes Mellitus.

Georgiana Ioana Potra Cicalău, Petru Aurel Babes, Horia Calniceanu, Adelina Popa, Gabriela Ciavoi, Gilda Mihaela Iova, Mariana Ganea, Ioana Scrobotă

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 1 pooled it
7.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 1 synthesis or guideline pooled it, 100 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Supercritical COPolymers · 2026
    Article
  4. Article
  5. Molecules (Basel, Switzerland) · 2026
    Article
  6. Review
  7. Article
  8. [Mechanism underlying carvacrol-induced alveolar bone repair via the phosphatidylinositol 3-kinase pathway in periodontal disease].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2026
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Analysis of Pharmacological Properties ofLife (Basel, Switzerland) · 2025
    Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Georgiana Ioana Potra CicalăuDoctoral School of Biomedical Science, University of Oradea, 1st University Street, 410087 Oradea, Romania.ORCID 0000-0002-8412-104X
Petru Aurel BabesDoctoral School of Biomedical Science, University of Oradea, 1st University Street, 410087 Oradea, Romania.
Horia CalniceanuDepartment of Periodontology, Faculty of Dental Medicine, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Adelina PopaDepartment of Orthodontics, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Gabriela CiavoiDepartment of Dental Medicine, Faculty of Medicine and Pharmacy, University of Oradea, 1st Decembrie Street, 410073 Oradea, Romania.
Gilda Mihaela IovaDepartment of Dental Medicine, Faculty of Medicine and Pharmacy, University of Oradea, 1st Decembrie Street, 410073 Oradea, Romania.
Mariana GaneaDepartment of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, 1st Decembrie Street, 410073 Oradea, Romania.
Ioana ScrobotăDepartment of Dental Medicine, Faculty of Medicine and Pharmacy, University of Oradea, 1st Decembrie Street, 410073 Oradea, Romania.ORCID 0000-0002-2643-761X
University of Oradea · ROVictor Babeș University of Medicine and Pharmacy Timișoara · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Periodontal disease and diabetes mellitus are two pathologies that are extremely widespread worldwide and share the feature of chronic inflammation. Carvacrol is a phenolic monoterpenoid, produced by a variety of herbs, the most well-known of which is

Indexed as

Anti-Inflammatory AgentsAntioxidantsBiphenyl CompoundsCymenesLignansAnimalsDiabetes MellitusHumansMagnoliaOriganumPeriodontitisAnti-Inflammatory AgentsAntioxidantsBiphenyl CompoundscarvacrolCymenesLignansmagnololanti-diabeticanti-inflammatoryantimicrobialanti-osteoclasticantioxidantcarvacroldiabetesmagnololperiodontitistoxicity

Identifiers

PMID34833990
PMCPMC8623889
OpenAlexW3213571939

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.