Evidence map›Paper›PMID 34833937›Full record

ReviewMolecules (Basel, Switzerland)2021

Insight into Potential Anticancer Activity of Algal Flavonoids: Current Status and Challenges.

Umme Tamanna Ferdous, Zetty Norhana Balia Yusof

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 68 citations in OpenAlex.

  1. Review
  2. Review
  3. Comparative evaluation of quercetin, rutin, and their nanoparticles: enhanced antimicrobial and antioxidant activities.International microbiology : the official journal of the Spanish Society for Microbiology · 2026
    Article
  4. Anticancer and Antimicrobial Activity ofMolecules (Basel, Switzerland) · 2026
    Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Anticancer Activity ofBiomolecules · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Prunin: An Emerging Anticancer Flavonoid.International journal of molecular sciences · 2025
    Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Toxicity of ZnFe-SOScientific reports · 2024
    Article
  19. Review
  20. The Potential of Algae in the Nutricosmetic Sector.Molecules (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Umme Tamanna FerdousAquatic Animal Health and Therapeutics Laboratory (AquaHealth), Institute of Bioscience, Universiti Putra Malaysia (UPM), Serdang 43400, Selangor, Malaysia.
Zetty Norhana Balia YusofAquatic Animal Health and Therapeutics Laboratory (AquaHealth), Institute of Bioscience, Universiti Putra Malaysia (UPM), Serdang 43400, Selangor, Malaysia.
Universiti Putra Malaysia · MY

Funding

Higher Institution Centre of Excellence (HICOE) Research Grant (Innovative Vaccines and Therapeutics against Fish Diseases) (Project No. 6369100) 6369100SATREPS (JICA-JST): COSMOS-MOHE G4-B Research Grant (Microalgae for Sustainable Aquaculture Health: Microalgae Vaccine Delivery System) (Project No. 6300866) 6300866
6 · The paper itself

Abstract

Flavonoids are some of the most precious phytochemicals, believed to be found largely in terrestrial plants. With the advancement of phytochemical research and marine bioprospecting, flavonoids have also been reported by the research of microalgae and macroalgae. High growth rate with minimal nutritional and growth requirement, saving arable land and rich metabolic profile make microalgae an excellent repertoire of novel anticancer compounds, such as flavonoids. In addition, marine algae, especially seaweeds contain different types of flavonoids which are assumed to have unique chemical structures and bioactivities than their terrestrial counterparts. Flavonoids are not only good antioxidants but also have the abilities to kill cancer cells by inducing apoptosis and autophagy. However, the study of the anticancer properties of flavonoids is largely limited to terrestrial plants. This review offers an insight into the distribution of different classes of flavonoids in eukaryotic microalgae, cyanobacteria and seaweeds with their possible anticancer activities. In addition, extraction and purification methods of these flavonoids have been highlighted. Finally, prospects and challenges to use algal flavonoids as anticancer agents have been discussed.

Indexed as

AnimalsAntineoplastic AgentsDrug DiscoveryFlavonoidsHumansMicroalgaeNeoplasmsSeaweedAntineoplastic AgentsFlavonoidsanticancerantioxidantflavonoidmicroalgaeseaweed

Identifiers

PMID34833937
PMCPMC8618413
OpenAlexW3212346948

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.