Evidence map›Paper›PMID 34833903›Full record

ArticleMolecules (Basel, Switzerland)2021

Molecular Insights into Binding Mode and Interactions of Structure-Based Virtually Screened Inhibitors for

Raed A H Almihyawi, Halah M H Al-Hasani, Tabarak Sabah Jassim, Ziyad Tariq Muhseen, Sitong Zhang, Guang Chen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Raed A H AlmihyawiCollege of Life Sciences, Jilin Agricultural University, Changchun 130118, China.
Halah M H Al-HasaniDepartment of Biotechnology, College of Science, University of Diyala, Baqubah 32001, Iraq.
Tabarak Sabah JassimDepartment of Prosthodontic Technologies, Dijlah University College, Baghdad 00964, Iraq.
Ziyad Tariq MuhseenSchool of Life Sciences, Shaanxi Normal University, Xi'an 710119, China.ORCID 0000-0001-7660-6461
Sitong ZhangCollege of Life Sciences, Jilin Agricultural University, Changchun 130118, China.
Guang ChenCollege of Life Sciences, Jilin Agricultural University, Changchun 130118, China.
Ministry of Education of the People's Republic of China · CNBaghdad Medical City · IQDijlah University College · IQShaanxi Normal University · CNUniversity of Diyala · IQ

Funding

Jilin Agricultural University 0000
6 · The paper itself

Abstract

Multi-drug resistance (MDR) bacterial pathogens pose a threat to global health and warrant the discovery of new therapeutic molecules, particularly those that can neutralize their virulence and stop the evolution of new resistant mechanisms. The superbug nosocomial pathogen,

Indexed as

Anti-Bacterial AgentsBacterial ProteinsBinding SitesDatabases, PharmaceuticalDrug DesignDrug Evaluation, PreclinicalDrug Resistance, Multiple, BacterialHumansHydrogen BondingHydrophobic and Hydrophilic InteractionsLigandsMicrobial Sensitivity TestsMolecular Dynamics SimulationPseudomonas aeruginosaSmall Molecule LibrariesUser-Computer InterfaceAnti-Bacterial AgentsBacterial ProteinsLigandsSmall Molecule LibrariesVirulence Factorsasinex antibacterial librarybinding free energiescomprehensive marine natural products databaseM64 controlmultiple virulence factor regulatorPseudomonas aeruginosa

Identifiers

PMID34833903
PMCPMC8619476
OpenAlexW3213565525

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.