Evidence map›Paper›PMID 34833883›Full record

ArticleMolecules (Basel, Switzerland)2021

60-nt DNA Direct Detection without Pretreatment by Surface-Enhanced Raman Scattering with Polycationic Modified Ag Microcrystal Derived from AgCl Cube.

Jikai Mao, Lvtao Huang, Li Fan, Fang Chen, Jingan Lou, Xuliang Shan, Dongdong Yu, Jianguang Zhou

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 65% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Jikai MaoResearch Center for Analytical Instrumentation, State Key Laboratory of Industrial Control Technology, Institute of Cyber-Systems and Control, Zhejiang University, Hangzhou 310027, China.
Lvtao HuangResearch Center for Analytical Instrumentation, State Key Laboratory of Industrial Control Technology, Institute of Cyber-Systems and Control, Zhejiang University, Hangzhou 310027, China.
Li FanResearch Center for Analytical Instrumentation, State Key Laboratory of Industrial Control Technology, Institute of Cyber-Systems and Control, Zhejiang University, Hangzhou 310027, China.
Fang ChenDepartment of Chemistry, Zhejiang University, Hangzhou 310027, China.
Jingan LouThe Children's Hospital Zhejiang University School of Medicine, Hangzhou 310000, China.
Xuliang ShanHangzhou Green Environment Science & Technology Co., Ltd., Hangzhou 310000, China.ORCID 0000-0001-6760-4990
Dongdong YuHospital of Zhejiang University, Hangzhou 310027, China.
Jianguang ZhouResearch Center for Analytical Instrumentation, State Key Laboratory of Industrial Control Technology, Institute of Cyber-Systems and Control, Zhejiang University, Hangzhou 310027, China.
State Key Laboratory of Industrial Control TechnologyChildren's Hospital of Zhejiang University · CNZhejiang Hospital · CNZhejiang University · CN

Funding

Key Research and Development Program Projects of Zhejiang Province 2018C03G2011156Research Project of the State Key Laboratory of Industrial Control Technology, Zhejiang University, China ICT1806
6 · The paper itself

Abstract

Direct detection of long-strand DNA by surface-enhanced Raman scattering (SERS) is a valuable method for diagnosis of hereditary diseases, but it is currently limited to less than 25-nt DNA strand in pure water, which makes this approach unsuitable for many real-life applications. Here, we report a 60-nt DNA label-free detection strategy without pretreatment by SERS with polyquaternium-modified Ag microcrystals derived from an AgCl cube. Through the reduction-induced decomposition, the size of the about 3 × 3 × 3 μm

Indexed as

DNAGoldMetal NanoparticlesNucleotidesSilverSpectrum Analysis, RamanDNAGoldNucleotidesSilver60-nt DNA direct detectionAg microcrystalpolycationicsurface-enhance Raman scattering

Identifiers

PMID34833883
PMCPMC8620099
OpenAlexW3213093633

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.