Evidence map›Paper›PMID 34833411›Full record

Trial reportMedicina (Kaunas, Lithuania)2021

Bone Marrow Aspirate Concentrate versus Platelet Rich Plasma or Hyaluronic Acid for the Treatment of Knee Osteoarthritis.

Oliver Dulic, Predrag Rasovic, Ivica Lalic, Vaso Kecojevic, Gordan Gavrilovic, Dzihan Abazovic, Dusan Maric, Mladen Miskulin, Marko Bumbasirevic

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Medicina (Kaunas, Lithuania), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07016672 (Efficacy of Therapy With Intra-articular Injections of PRP Compared With Therapy With Intra-articular Injections of HA, in Patients With Grade III or IV GONArthrosis), which is not on this map. Cited by 59 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 10 pooled it
13.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07016672 narecruitingnot on this mapstarted 2025, after this paper: background citation

Efficacy of Therapy With Intra-articular Injections of PRP Compared With Therapy With Intra-articular Injections of HA, in Patients With Grade III or IV GONArthrosis: a Prospective Randomized Open-label Study

TypeinterventionalSponsorCentre Hospitalier Intercommunal de Toulon La Seyne sur MerRan2025 to 2028Enrolled150ConditionsKnee OsteoarthritisArmsintra-articular injection of HA, intra-articular injection of PRP
3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 10 syntheses or guidelines pooled it, 91 citations in OpenAlex.

  1. Pooled it
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  3. Bone marrow aspirate concentrate adjunct for acetabular labral tear repair: a systematic review and meta-analysis.Hip international : the journal of clinical and experimental research on hip pathology and therapy · 2025
    Pooled it
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  11. Trial
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  14. Review
  15. Article
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  19. Adipose-derived and bone marrow aspirate concentrate injections for osteoarthritis: A scoping review.PM & R : the journal of injury, function, and rehabilitation · 2026
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Oliver DulicMedical Faculty, University of Belgrade, 11000 Belgrade, Serbia.ORCID 0000-0002-5914-9956
Predrag RasovicDepartment for Orthopedic Surgery and Traumatology, Clinical Center of Vojvodina, Hajduk Veljkova 1-9, 21000 Novi Sad, Serbia.
Ivica LalicDepartment for Orthopedic Surgery and Traumatology, Clinical Center of Vojvodina, Hajduk Veljkova 1-9, 21000 Novi Sad, Serbia.
Vaso KecojevicDepartment for Orthopedic Surgery and Traumatology, Clinical Center of Vojvodina, Hajduk Veljkova 1-9, 21000 Novi Sad, Serbia.
Gordan GavrilovicAtlas Hospital, 11000 Belgrade, Serbia.
Dzihan AbazovicRenova Hospital Belgrade, 11000 Belgrade, Serbia.
Dusan MaricMedical Faculty, University of Novi Sad, 21000 Novi Sad, Serbia.
Mladen MiskulinSpecijalna Bolnica za Neurokirurgiju i Ortopediju Aksis, 10000 Zagreb, Croatia.
Marko BumbasirevicMedical Faculty, University of Belgrade, 11000 Belgrade, Serbia.
University of Novi Sad · RSKlinički centar Vojvodine · RSKlinika za psihijatriju Vrapče · HRUniversity of Belgrade · RS

Funding

Provincial Government of Vojvodina, New technologies in Medicine 231-3/2016
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Osteoarthritis, KneePlatelet-Rich PlasmaBone MarrowHumansHyaluronic AcidTreatment OutcomeHyaluronic Acidbone marrow aspirate concentratehyaluronic acidknee osteoarthritisplatelet rich plasmaregenerative medicinestem cells

Identifiers

PMID34833411
PMCPMC8623697
OpenAlexW3209017909

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.