Evidence map›Paper›PMID 34833214›Full record

ArticlePolymers2021

Characterisation and Modelling of an Artificial Lens Capsule Mimicking Accommodation of Human Eyes.

Huidong Wei, James S Wolffsohn, Otavio Gomes de Oliveira, Leon N Davies

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Huidong WeiCollege of Health and Life Sciences, Aston University, Birmingham B4 7ET, UK.ORCID 0000-0002-6420-3216
James S WolffsohnCollege of Health and Life Sciences, Aston University, Birmingham B4 7ET, UK.ORCID 0000-0003-4673-8927
Otavio Gomes de OliveiraRayner Intraocular Lenses Limited, Worthing BN14 8AQ, UK.
Leon N DaviesCollege of Health and Life Sciences, Aston University, Birmingham B4 7ET, UK.ORCID 0000-0002-1554-0566
Aston University · GB

Funding

Innovate UK 11718
6 · The paper itself

Abstract

A synthetic material of silicone rubber was used to construct an artificial lens capsule (ALC) in order to replicate the biomechanical behaviour of human lens capsule. The silicone rubber was characterised by monotonic and cyclic mechanical tests to reveal its hyper-elastic behaviour under uniaxial tension and simple shear as well as the rate independence. A hyper-elastic constitutive model was calibrated by the testing data and incorporated into finite element analysis (FEA). An experimental setup to simulate eye focusing (accommodation) of ALC was performed to validate the FEA model by evaluating the shape change and reaction force. The characterisation and modelling approach provided an insight into the intrinsic behaviour of materials, addressing the inflating pressure and effective stretch of ALC under the focusing process. The proposed methodology offers a virtual testing environment mimicking human capsules for the variability of dimension and stiffness, which will facilitate the verification of new ophthalmic prototype such as accommodating intraocular lenses (AIOLs).

Indexed as

biomechanicalconstitutive modelFEAhyper-elasticsilicone rubber

Identifiers

PMID34833214
PMCPMC8619262
OpenAlexW3212533821

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.