Synthesis of Functional Building Blocks for Type III-B Rotaxane Dendrimer.

Chak-Shing Kwan, Watson K-W Ho, Yanyan Chen, Zongwei Cai, Ken Cham-Fai Leung

Abstract read

In one paragraph

Article in Polymers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chak-Shing KwanState Key Laboratory of Environmental and Biological Analysis, Department of Chemistry, The Hong Kong Baptist University, Kowloon Tong, Kowloon, Hong Kong, China.ORCID 0000-0002-1289-6620

Watson K-W HoDepartment of Chemistry, The Chinese University of Hong Kong, Shatin, NT, Hong Kong, China.

Yanyan ChenState Key Laboratory of Environmental and Biological Analysis, Department of Chemistry, The Hong Kong Baptist University, Kowloon Tong, Kowloon, Hong Kong, China.

Zongwei CaiState Key Laboratory of Environmental and Biological Analysis, Department of Chemistry, The Hong Kong Baptist University, Kowloon Tong, Kowloon, Hong Kong, China.

Ken Cham-Fai LeungState Key Laboratory of Environmental and Biological Analysis, Department of Chemistry, The Hong Kong Baptist University, Kowloon Tong, Kowloon, Hong Kong, China.ORCID 0000-0002-0349-0418

Funding

Hong Kong Baptist University RC-KRPS-20-21/02

6 · The paper itself

Abstract

Second-generation type III-B rotaxane dendrons, equipped with succinimide and acetylene functional groups, were synthesized successfully and characterized by NMR spectroscopy and mass spectrometry. A cell viability study of a dendron with a normal cell line of L929 fibroblast cells revealed no obvious cytotoxicity at a range of 5 to 100 μM. The nontoxic properties of the sophisticated rotaxane dendron building blocks provided a choice of bio-compatible macromolecular machines that could be potentially developed into polymeric materials.

Indexed as

crown etherfibroblastfunctional dendronmacromolecular machinerotaxane dendrimer

Identifiers

PMID34833208

DOI10.3390/polym13223909

PMCPMC8622516

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.