Evidence map›Paper›PMID 34833061›Full record

ArticleLife (Basel, Switzerland)2021

Genome-Wide Scanning of Potential Hotspots for Adenosine Methylation: A Potential Path to Neuronal Development.

Sanjay Kumar, Lung-Wen Tsai, Pavan Kumar, Rajni Dubey, Deepika Gupta, Anjani Kumar Singh, Vishnu Swarup, Himanshu Narayan Singh

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 3 countries.

Sanjay KumarDepartment of Life Sciences, School of Basic Sciences and Research, Sharda University, Greater Noida 201310, India.ORCID 0000-0001-6296-0291
Lung-Wen TsaiDepartment of Medicine Research, Taipei Medical University Hospital, Taipei 11031, Taiwan.ORCID 0000-0002-3541-5834
Pavan KumarDepartment of Anatomy, All India Institute of Medical Sciences, New Delhi 110029, India.
Rajni DubeyDepartment of Medicine Research, Taipei Medical University Hospital, Taipei 11031, Taiwan.ORCID 0000-0002-0506-7744
Deepika GuptaDepartment of Neurology, All India Institute of Medical Sciences, New Delhi 110029, India.
Anjani Kumar SinghDepartment of Physics, Atma Ram Sanatan Dharma College, University of Delhi, New Delhi 110021, India.ORCID 0000-0003-1764-0656
Vishnu SwarupDepartment of Neurology, All India Institute of Medical Sciences, New Delhi 110029, India.
Himanshu Narayan SinghDepartment of System Biology, Columbia University Irving Medical Center, New York, NY 10032, USA.
All India Institute of Medical Sciences · INTaipei Medical University Hospital · TWColumbia University Irving Medical Center · USSharda University · INUniversity of Delhi · INUniversity of Illinois Chicago · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methylation of adenosines at N6 position (m6A) is the most frequent internal modification in mRNAs of the human genome and attributable to diverse roles in physiological development, and pathophysiological processes. However, studies on the role of m6A in neuronal development are sparse and not well-documented. The m6A detection remains challenging due to its inconsistent pattern and less sensitivity by the current detection techniques. Therefore, we applied a sliding window technique to identify the consensus site (5'-GGACT-3')

Indexed as

adenosine methylationm6Aneuronal developmentRNA modification

Identifiers

PMID34833061
PMCPMC8618456
OpenAlexW3210090099

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.