Evidence map›Paper›PMID 34833052›Full record

ArticleLife (Basel, Switzerland)2021

Build-a-Cell: Engineering a Synthetic Cell Community.

Caroline Frischmon, Carlise Sorenson, Michael Winikoff, Katarzyna P Adamala

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Review
  3. A synthetic cell phage cycle.Nature communications · 2025
    Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Light energy transduction in liposome-based artificial cells.Frontiers in bioengineering and biotechnology · 2023
    Review
  9. Cell-Free Production Systems in Droplet Microfluidics.Advances in biochemical engineering/biotechnology · 2023
    Review
  10. Review
  11. Article
  12. A four-track perspective for bottom-up synthetic cells.Frontiers in bioengineering and biotechnology · 2022
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Caroline FrischmonScience Communication Lab., BioTechnology Institute, University of Minnesota, Minneapolis, MN 55108, USA.
Carlise SorensonDepartment of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, MN 55455, USA.
Michael WinikoffScience Communication Lab., BioTechnology Institute, University of Minnesota, Minneapolis, MN 55108, USA.
Katarzyna P AdamalaDepartment of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, MN 55455, USA.

Funding

National Science Foundation Research Coordination Network 1901145
6 · The paper itself

Abstract

Build-a-Cell is a global network of researchers that aims to develop synthetic living cells within the next decade. These cells will revolutionize the biotechnology industry by providing scientists and engineers with a more complete understanding of biology. Researchers can already replicate many cellular functions individually, but combining them into a single cell remains a significant challenge. This integration step will require the type of large-scale collaboration made possible by Build-a-Cell's open, collective structure. Beyond the lab, Build-a-Cell addresses policy issues and biosecurity concerns associated with synthetic cells. The following review discusses Build-a-Cell's history, function, and goals.

Indexed as

artificial lifebioengineeringcell-freeliposomessynthetic biologysynthetic cells

Identifiers

PMID34833052
PMCPMC8618533

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.