Evidence map›Paper›PMID 34832963›Full record

ArticlePharmaceuticals (Basel, Switzerland)2021

Physicochemical and Biological Characterization of rhC1INH Expressed in CHO Cells.

Ekaterina Zubareva, Maksim Degterev, Alexander Kazarov, Maria Zhiliaeva, Ksenia Ulyanova, Vladimir Simonov, Ivan Lyagoskin, Maksim Smolov, Madina Iskakova, Anna Azarova and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ekaterina ZubarevaJSC "GENERIUM", 14, Vladimirskaya Street, Volginskiy 601125, Vladimir Region, Russia.ORCID 0000-0002-6178-0050
Maksim DegterevJSC "GENERIUM", 14, Vladimirskaya Street, Volginskiy 601125, Vladimir Region, Russia.ORCID 0000-0002-5541-5575
Alexander KazarovJSC "GENERIUM", 14, Vladimirskaya Street, Volginskiy 601125, Vladimir Region, Russia.ORCID 0000-0003-0682-6113
Maria ZhiliaevaJSC "GENERIUM", 14, Vladimirskaya Street, Volginskiy 601125, Vladimir Region, Russia.ORCID 0000-0002-9880-1724
Ksenia UlyanovaJSC "GENERIUM", 14, Vladimirskaya Street, Volginskiy 601125, Vladimir Region, Russia.ORCID 0000-0002-3793-7978
Vladimir SimonovJSC "GENERIUM", 14, Vladimirskaya Street, Volginskiy 601125, Vladimir Region, Russia.
Ivan LyagoskinJSC "GENERIUM", 14, Vladimirskaya Street, Volginskiy 601125, Vladimir Region, Russia.ORCID 0000-0002-9058-1106
Maksim SmolovJSC "GENERIUM", 14, Vladimirskaya Street, Volginskiy 601125, Vladimir Region, Russia.ORCID 0000-0003-2935-7655
Madina IskakovaJSC "GENERIUM", 14, Vladimirskaya Street, Volginskiy 601125, Vladimir Region, Russia.ORCID 0000-0001-9527-8176
Anna AzarovaJSC "GENERIUM", 14, Vladimirskaya Street, Volginskiy 601125, Vladimir Region, Russia.
Rahim ShukurovJSC "GENERIUM", 14, Vladimirskaya Street, Volginskiy 601125, Vladimir Region, Russia.ORCID 0000-0002-6532-7835

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The disfunction or deficiency of the C1 esterase inhibitor (C1INH) is associated with hereditary or acquired angioedema (HAE/AAE), a rare life-threatening condition characterized by swelling in the skin, respiratory and gastrointestinal tracts. The current treatment options may carry the risks of either viral infection (plasma-derived Berinert

Indexed as

acquired angioedema (AAE)analytical methodsBerinert®C1 inhibitorcharacterizationCHO cellshereditary angioedema (HAE)rhC1INHRuconest®

Identifiers

PMID34832963
PMCPMC8621594
OpenAlexW3214928623

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.