Evidence map›Paper›PMID 34832916›Full record

ArticlePharmaceuticals (Basel, Switzerland)2021

Novel Small Molecule Inhibitors That Prevent the Neuroparalysis of Tetanus Neurotoxin.

Giulia Zanetti, Andrea Mattarei, Florigio Lista, Ornella Rossetto, Cesare Montecucco, Marco Pirazzini

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Giulia ZanettiDepartment of Biomedical Sciences, University of Padova, Via U. Bassi 58/B, 35121 Padova, Italy.ORCID 0000-0001-9350-1047
Andrea MattareiDepartment of Pharmaceutical and Pharmacological Sciences, University of Padova, Via F. Marzolo 5, 35131 Padova, Italy.ORCID 0000-0002-2023-0749
Florigio ListaScientific Department, Army Medical Center, Via Santo Stefano Rotondo 4, 00184 Rome, Italy.
Ornella RossettoDepartment of Biomedical Sciences, University of Padova, Via U. Bassi 58/B, 35121 Padova, Italy.
Cesare MontecuccoDepartment of Biomedical Sciences, University of Padova, Via U. Bassi 58/B, 35121 Padova, Italy.
Marco PirazziniDepartment of Biomedical Sciences, University of Padova, Via U. Bassi 58/B, 35121 Padova, Italy.ORCID 0000-0003-4127-254X
University of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tetanus neurotoxin (TeNT) is a protein exotoxin produced by

Indexed as

disulfide reductionEGAtetanus neurotoxinthioredoxin system inhibitorstrafficking

Identifiers

PMID34832916
PMCPMC8618345
OpenAlexW3212538845

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.