ArticlePharmaceuticals (Basel, Switzerland)2021
Quantification of Degradation Products Formed during Heat Sterilization of Glucose Solutions by LC-MS/MS: Impact of Autoclaving Temperature and Duration on Degradation.
Article in Pharmaceuticals (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 29 citations in OpenAlex.
- Selection of the best method for inherent tannin reduction and high nutrient retention.The Onderstepoort journal of veterinary research · 2026Article
- Evaluating Dextrose-Derived Interference in Low-Concentration Monoclonal Antibody Quantification for Clinical In-Use Studies.AAPS PharmSciTech · 2026Article
- Evaluating Dextrose-Derived Interference in Low-Concentration Monoclonal Antibody Quantification for Clinical In-Use Studies.AAPS PharmSciTech · 2026Article
- Selective Quenching of Peracetic Acid by Sodium Dithionite Enables Rapid, Non-Thermal Sterilization forMicroorganisms · 2026Article
- Discovery of a MarineMarine drugs · 2026Article
- Heat-processed rodent chow alters nutritive content and improves metabolic outcomes in insulin-resistant female mice.Frontiers in nutrition · 2026Article
- Comparison of sterilisation methods for deer velvet antler extracts and their impact on anticancer activity.Frontiers in pharmacology · 2026Article
- Effects of combinatorial hurdles on a non-alcoholic beer matrix challenged withFrontiers in microbiology · 2026Article
- Optimization of In Vitro Ovule Culture System in Upland Cotton.Plants (Basel, Switzerland) · 2025Article
- Phenolic Exudation Control and Indirect Somatic Embryogenesis of Garlic-Fruit Tree (Plants (Basel, Switzerland) · 2025Article
- Thidiazuron andFrontiers in plant science · 2025Article
- Article
- Development of a new sterilization method for microalgae media using calcium hypochlorite as the sterilant.Bioprocess and biosystems engineering · 2024Article
- Plant Growth Regulation in Cell and Tissue Culture In Vitro.Plants (Basel, Switzerland) · 2024Review
- Protocol to perform dynamic microfluidic single-cell cultivation of C. glutamicum.STAR protocols · 2023Article
- Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Heat sterilization of glucose solutions can lead to the formation of various glucose degradation products (GDPs) due to oxidation, hydrolysis, and dehydration. GDPs can have toxic effects after parenteral administration due to their high reactivity. In this study, the application of the F0 concept to modify specific time/temperature models during heat sterilization and their influence on the formation of GDPs in parenteral glucose solutions was investigated using high-performance liquid chromatography-tandem mass spectrometry (LC-MS/MS). Glucose solutions (10%,
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.