ReviewPharmaceuticals (Basel, Switzerland)2021
Lipid Nanoparticulate Drug Delivery Systems: Recent Advances in the Treatment of Skin Disorders.
Review in Pharmaceuticals (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed.
- Nanotechnologies for Skin Drug Delivery: Polymeric, Bio-Based, and Hybrid Nanocarriers with Clinical and Translational Perspectives.Pharmaceuticals (Basel, Switzerland) · 2026Review
- A Competent Antiviral, Antimicrobial, Nontoxic Nanostructured Lipid Carrier System for Safe Use as a Hand Sanitizer: In Vitro and In Vivo Studies.Biomolecules · 2026Article
- Numerical modelling for hollow pyramidal microneedle-based drug-loaded particles delivery for controlled drug release.Drug delivery and translational research · 2026Article
- Nanotechnology in Dermatology: A Comprehensive Narrative Review of Performance, Safety, and Clinical Translation.Health science reports · 2026Article
- Topical Astaxanthin Attenuates Imiquimod-Induced Psoriasiform Dermatitis by Downregulating Psoriasis-Associated Keratin Gene Expression (Krt16, Krt17, Krt6a) and Inhibiting the JAK-STAT Signaling Pathway.Molecules (Basel, Switzerland) · 2026Article
- Nanoformulations of essential oils for the treatment of fungal diseases, with a focus on dermatophytes.Archives of microbiology · 2026Review
- Review
- Synergy between Antimicrobial Peptides and Lipid Nanoparticles for Skin Infection Control.ACS applied materials & interfaces · 2026Review
- Niosome-mediated melatonin delivery via SilMA/GelMA microneedles promotes healing of sleep deprivation-aggravated oral ulcers.Regenerative biomaterials · 2026Article
- A Comprehensive Review on Oleic Acid Vesicles: A Novel Approach to Drug Delivery.Pharmaceutical nanotechnology · 2026Review
- Combating Gram-negative infections: The role of antimicrobial peptides and nanotechnology in overcoming antibiotic resistance.Materials today. Bio · 2025Review
- Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy.Scientific reports · 2025Article
- Vitamin D-loaded lipid nanoparticles: antioxidant properties, preparation, optimization, and in vitro characterization.Drug delivery and translational research · 2025Article
- Development and Characterization of Topical Gels Containing Lipid Nanosystems Loaded withGels (Basel, Switzerland) · 2025Article
- Advances in Transdermal Drug Delivery Systems and Clinical Applications in Inflammatory Skin Diseases.Pharmaceutics · 2025Review
- Anti-Inflammasome Effect of Impressic Acid on Diesel Exhaust Particulate Matter-Induced NLRP1 Inflammasome via the Keap1/p62/Nrf2-Signaling Pathway in Keratinocytes.Antioxidants (Basel, Switzerland) · 2025Article
- Lipid Nanoparticles Carrying Essential Oils for Multiple Applications as Antimicrobials.Pharmaceutics · 2025Review
- Topical Administration of Nanostructured Lipid Carriers as a Viable Approach to Reduce Inflammation: A Review.Anti-inflammatory & anti-allergy agents in medicinal chemistry · 2025Review
- Revolutionizing Antibacterial Strategies: Lipid Nanoparticles as Game-changers in Combatting Multi-drug-resistant Infections.Current medicinal chemistry · 2025Review
- Nanocarrier-Based Transdermal Drug Delivery Systems for Dermatological Therapy.Pharmaceutics · 2024Review
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
The multifunctional role of the human skin is well known. It acts as a sensory and immune organ that protects the human body from harmful environmental impacts such as chemical, mechanical, and physical threats, reduces UV radiation effects, prevents moisture loss, and helps thermoregulation. In this regard, skin disorders related to skin integrity require adequate treatment. Lipid nanoparticles (LN) are recognized as promising drug delivery systems (DDS) in treating skin disorders. Solid lipid nanoparticles (SLN) together with nanostructured lipid carriers (NLC) exhibit excellent tolerability as these are produced from physiological and biodegradable lipids. Moreover, LN applied to the skin can improve stability, drug targeting, occlusion, penetration enhancement, and increased skin hydration compared with other drug nanocarriers. Furthermore, the features of LN can be enhanced by inclusion in suitable bases such as creams, ointments, gels (i.e., hydrogel, emulgel, bigel), lotions, etc. This review focuses on recent developments in lipid nanoparticle systems and their application to treating skin diseases. We point out and consider the reasons for their creation, pay attention to their advantages and disadvantages, list the main production techniques for obtaining them, and examine the place assigned to them in solving the problems caused by skin disorders.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.