Evidence map›Paper›PMID 34832813›Full record

ArticleMicromachines2021

Microvalve with Trapezoid-Shaped Cross-Section for Deep Microchannels.

Maho Kaminaga, Tadashi Ishida, Toru Omata

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Micromachines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Maho KaminagaDepartment of Mechanical Engineering, National Institute of Technology, Toyota College, 2-1 Eiseicho, Toyota 471-0067, Japan.ORCID 0000-0003-2848-2323
Tadashi IshidaDepartment of Mechanical Engineering, School of Engineering, Tokyo Institute of Technology, 12-1 Ookayama, Tokyo 152-8550, Japan.ORCID 0000-0002-7380-8145
Toru OmataDepartment of Mechanical Engineering, School of Engineering, Tokyo Institute of Technology, 12-1 Ookayama, Tokyo 152-8550, Japan.

Funding

Japan Society for the Promotion of Science 16H02320Takahashi Industrial and Economic Research Foundation 143
6 · The paper itself

Abstract

Simple microfluidic systems for handling large particles such as three-dimensional (3D) cultured cells, microcapsules, and animalcules have contributed to the advancement of biology. However, obtaining a highly integrated microfluidic device for handling large particles is difficult because there are no suitable microvalves for deep microchannels. Therefore, this study proposes a microvalve with a trapezoid-shaped cross-section to close a deep microchannel. The proposed microvalve can close a 350 μm deep microchannel, which is suitable for handling hundreds of micrometer-scale particles. A double-inclined lithography process was used to fabricate the trapezoid-shaped cross-section. The microvalve was fabricated by bonding three polydimethylsiloxane layers: a trapezoid-shaped liquid channel layer, a membrane, and a pneumatic channel layer. The pneumatic balloon, consisting of the membrane and the pneumatic channel, was located beneath a trapezoid-shaped cross-section microchannel. The valve was operated by the application of pneumatic pressure to the pneumatic channel. We experimentally confirmed that the expansion of the pneumatic balloon could close the 350 μm deep microchannel.

Indexed as

inclined lithographymicrofluidic devicepneumatic microvalve

Identifiers

PMID34832813
PMCPMC8622413

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.