Evidence map›Paper›PMID 34832799›Full record

ArticleMicromachines2021

Isothermal Recombinase Polymerase Amplification (RPA) of

Maria Georgoutsou-Spyridonos, Myrto Filippidou, Georgia D Kaprou, Dimitrios C Mastellos, Stavros Chatzandroulis, Angeliki Tserepi

Open access · goldAbstract read
In one paragraph

Article in Micromachines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Maria Georgoutsou-SpyridonosInstitute of Nanoscience and Nanotechnology, NCSR-Demokritos, Patriarchou Gregoriou E' and 27 Neapoleos Str., Aghia Paraskevi, Attiki, 15341 Athens, Greece.
Myrto FilippidouInstitute of Nanoscience and Nanotechnology, NCSR-Demokritos, Patriarchou Gregoriou E' and 27 Neapoleos Str., Aghia Paraskevi, Attiki, 15341 Athens, Greece.
Georgia D KaprouInstitute of Nanoscience and Nanotechnology, NCSR-Demokritos, Patriarchou Gregoriou E' and 27 Neapoleos Str., Aghia Paraskevi, Attiki, 15341 Athens, Greece.ORCID 0000-0002-2543-6287
Dimitrios C MastellosInstitute of Nuclear & Radiological Sciences and Technology, Energy & Safety, NCSR-Demokritos, Patriarchou Gregoriou E' and 27 Neapoleos Str., Aghia Paraskevi, Attiki, 15341 Athens, Greece.ORCID 0000-0002-6634-3271
Stavros ChatzandroulisInstitute of Nanoscience and Nanotechnology, NCSR-Demokritos, Patriarchou Gregoriou E' and 27 Neapoleos Str., Aghia Paraskevi, Attiki, 15341 Athens, Greece.
Angeliki TserepiInstitute of Nanoscience and Nanotechnology, NCSR-Demokritos, Patriarchou Gregoriou E' and 27 Neapoleos Str., Aghia Paraskevi, Attiki, 15341 Athens, Greece.
National Centre of Scientific Research "Demokritos" · GR

Funding

European Regional Development Fund of the European Union and Greek national funds through the Operational Program Competitiveness, Entrepreneurship and Innovation T1EDK-03565
6 · The paper itself

Abstract

Printed circuit board (PCB) technology has been recently proposed as a convenient platform for seamlessly integrating electronics and microfluidics in the same substrate, thus facilitating the introduction of integrated and low-cost microfluidic devices to the market, thanks to the inherent upscaling potential of the PCB industry. Herein, a microfluidic chip, encompassing on PCB both a meandering microchannel and microheaters to accommodate recombinase polymerase amplification (RPA), is designed and commercially fabricated for the first time on PCB. The developed microchip is validated for RPA-based amplification of two

Indexed as

DNA amplificationE. colimicrofluidicsmicroheatersmolecular diagnosticsPCB technologyRPA

Identifiers

PMID34832799
PMCPMC8619769
OpenAlexW3213321780

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.