Evidence map›Paper›PMID 34832776›Full record

ArticleMicromachines2021

Manufacturing Process of Polymeric Microneedle Sensors for Mass Production.

Jae Yun Baek, Kyung Mook Kang, Hyeong Jun Kim, Ju Hyeon Kim, Ju Hwan Lee, Gilyong Shin, Jei Gyeong Jeon, Junho Lee, Yusu Han, Byeong Jun So and 1 more

Open access · goldAbstract read
In one paragraph

Article in Micromachines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Jae Yun BaekAdvanced Materials Lab, Department of Mechanical Engineering, Inha University, Incheon 22212, Korea.
Kyung Mook KangAdvanced Materials Lab, Department of Mechanical Engineering, Inha University, Incheon 22212, Korea.
Hyeong Jun KimAdvanced Materials Lab, Department of Mechanical Engineering, Inha University, Incheon 22212, Korea.
Ju Hyeon KimAdvanced Materials Lab, Department of Mechanical Engineering, Inha University, Incheon 22212, Korea.
Ju Hwan LeeAdvanced Materials Lab, Department of Mechanical Engineering, Inha University, Incheon 22212, Korea.
Gilyong ShinAdvanced Materials Lab, Department of Mechanical Engineering, Inha University, Incheon 22212, Korea.
Jei Gyeong JeonAdvanced Materials Lab, Department of Mechanical Engineering, Inha University, Incheon 22212, Korea.
Junho LeeAdvanced Materials Lab, Department of Mechanical Engineering, Inha University, Incheon 22212, Korea.
Yusu HanAdvanced Materials Lab, Department of Mechanical Engineering, Inha University, Incheon 22212, Korea.
Byeong Jun SoAdvanced Materials Lab, Department of Mechanical Engineering, Inha University, Incheon 22212, Korea.
Tae June KangAdvanced Materials Lab, Department of Mechanical Engineering, Inha University, Incheon 22212, Korea.
Inha University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this work, we present a fabrication process for microneedle sensors made of polylactic acid (PLA), which can be utilized for the electrochemical detection of various biomarkers in interstitial fluid. Microneedles were fabricated by the thermal compression molding of PLA into a laser machined polytetrafluoroethylene (PTFE) mold. Sensor fabrication was completed by forming working, counter, and reference electrodes on each sensor surface by Au sputtering through a stencil mask, followed by laser dicing to separate individual sensors from the substrate. The devised series of processes was designed to be suitable for mass production, where multiple microneedle sensors can be produced at once on a 4-inch wafer. The operational stability of the fabricated sensors was confirmed by linear sweep voltammetry and cyclic voltammetry at the range of working potentials of various biochemical molecules in interstitial fluid.

Indexed as

biomoleculeselectrochemical detectionlaser machiningmicroneedlepolylactic acid

Identifiers

PMID34832776
PMCPMC8624934
OpenAlexW3211340971

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.