Evidence map›Paper›PMID 34832651›Full record

ArticlePathogens (Basel, Switzerland)2021

Roles of OmpA in Type III Secretion System-Mediated Virulence of Enterohemorrhagic

Hidetada Hirakawa, Kazutomo Suzue, Ayako Takita, Haruyoshi Tomita

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Surface proteins of Shiga toxin-producingFrontiers in microbiology · 2023
    Article
  8. New Insights into Bacterial Pathogenesis.Pathogens (Basel, Switzerland) · 2022
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Hidetada HirakawaDepartment of Bacteriology, Graduate School of Medicine, Gunma University, Maebashi 371-8511, Gunma, Japan.
Kazutomo SuzueDepartment of Infectious Diseases and Host Defense, Graduate School of Medicine, Gunma University, Maebashi 371-8511, Gunma, Japan.ORCID 0000-0002-8959-5746
Ayako TakitaDepartment of Bacteriology, Graduate School of Medicine, Gunma University, Maebashi 371-8511, Gunma, Japan.
Haruyoshi TomitaDepartment of Bacteriology, Graduate School of Medicine, Gunma University, Maebashi 371-8511, Gunma, Japan.
Gunma University · JP

Funding

Japan Agency for Medical Research and Development 21fk0108604h0901Japan Society for the Promotion of Science 19K07533
6 · The paper itself

Abstract

Outer membrane proteins are commonly produced by gram-negative bacteria, and they have diverse functions. A subgroup of proteins, which includes OmpA, OmpW and OmpX, is often involved in bacterial pathogenesis. Here we show that OmpA, rather than OmpW or OmpX, contributes to the virulence of enterohemorrhagic

Indexed as

enteric pathogengastrointestinal infectionouter membrane proteinpathogenicitytype III secretion systemvirulence

Identifiers

PMID34832651
PMCPMC8622347
OpenAlexW3212497301

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.