Evidence map›Paper›PMID 34832648›Full record

ReviewPathogens (Basel, Switzerland)2021

Molecular and Clinical Aspects of Chronic Manifestations in Chagas Disease: A State-of-the-Art Review.

Germán J Medina-Rincón, Sebastián Gallo-Bernal, Paula A Jiménez, Lissa Cruz-Saavedra, Juan David Ramírez, María Juliana Rodríguez, Ramón Medina-Mur, Gustavo Díaz-Nassif, María Daniela Valderrama-Achury, Héctor M Medina

Abstract readReview
In one paragraph

Review in Pathogens (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Long-Term Parasitological Clearance and Cardiac Progression inTropical medicine and infectious disease · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. An Update on Vaccines AgainstPathogens (Basel, Switzerland) · 2025
    Review
  14. Article
  15. Molecular Markers for the Phylogenetic Reconstruction ofPathogens (Basel, Switzerland) · 2025
    Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Germán J Medina-RincónSchool of Medicine and Health Sciences, Universidad del Rosario, Bogotá 111221, Colombia.ORCID 0000-0003-2874-3669
Sebastián Gallo-BernalSchool of Medicine and Health Sciences, Universidad del Rosario, Bogotá 111221, Colombia.ORCID 0000-0003-4531-3783
Paula A JiménezCentro de Investigaciones en Microbiología y Biotecnología-UR (CIMBIUR), Facultad de Ciencias Naturales, Universidad del Rosario, Bogotá 111221, Colombia.
Lissa Cruz-SaavedraCentro de Investigaciones en Microbiología y Biotecnología-UR (CIMBIUR), Facultad de Ciencias Naturales, Universidad del Rosario, Bogotá 111221, Colombia.
Juan David RamírezCentro de Investigaciones en Microbiología y Biotecnología-UR (CIMBIUR), Facultad de Ciencias Naturales, Universidad del Rosario, Bogotá 111221, Colombia.ORCID 0000-0002-1344-9312
María Juliana RodríguezDivision of Cardiology, Fundación Cardioinfantil-Instituto de Cardiología, Bogotá 110131, Colombia.
Ramón Medina-MurDivision of Cardiology, Fundación Cardioinfantil-Instituto de Cardiología, Bogotá 110131, Colombia.ORCID 0000-0001-7161-1587
Gustavo Díaz-NassifDivision of Gastroenterology and Liver Diseases, Fundación Cardioinfantil-Instituto de Cardiología, Bogotá 111221, Colombia.
María Daniela Valderrama-AchurySchool of Medicine and Health Sciences, Universidad del Rosario, Bogotá 111221, Colombia.
Héctor M MedinaSchool of Medicine and Health Sciences, Universidad del Rosario, Bogotá 111221, Colombia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic manifestations of Chagas disease present as disabling and life-threatening conditions affecting mainly the cardiovascular and gastrointestinal systems. Although meaningful research has outlined the different molecular mechanisms underlying

Indexed as

achalasiacardiomyopathyChagas diseaseheart failuremegacolonTrypanosoma cruzivector-borne disease

Identifiers

PMID34832648
PMCPMC8619182

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.