Evidence map›Paper›PMID 34832557›Full record

ArticlePathogens (Basel, Switzerland)2021

Analysis of

Maude Dagenais, Jared Q Gerlach, George R Wendt, James J Collins, Louise E Atkinson, Angela Mousley, Timothy G Geary, Thavy Long

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Deciphering theBiomolecules · 2025
    Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. SialylatedJournal of extracellular biology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 4 countries.

Maude DagenaisInstitute of Parasitology, McGill University, Ste-Anne-de-Bellevue, QC H9X 3V9, Canada.ORCID 0000-0001-7004-1893
Jared Q GerlachGlycoscience Group, Advanced Glycoscience Research Cluster, National Centre for Biomedical Engineering Science, National University of Ireland Galway, H91 TK33 Galway, Ireland.
George R WendtDepartment of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
James J CollinsDepartment of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.ORCID 0000-0001-5237-1004
Louise E AtkinsonMicrobes and Pathogen Biology, The Institute for Global Food Security, School of Biological Sciences, Queen's University-Belfast, Belfast BT9 5DL, UK.
Angela MousleyMicrobes and Pathogen Biology, The Institute for Global Food Security, School of Biological Sciences, Queen's University-Belfast, Belfast BT9 5DL, UK.
Timothy G GearyInstitute of Parasitology, McGill University, Ste-Anne-de-Bellevue, QC H9X 3V9, Canada.
Thavy LongInstitute of Parasitology, McGill University, Ste-Anne-de-Bellevue, QC H9X 3V9, Canada.
Queen's University Belfast · GBMcGill University · CAThe University of Texas Southwestern Medical Center · USOllscoil na Gaillimhe – University of Galway · IE

Funding

The Biology of Stem Cells in the Human Parasite Schistosoma MansoniR01AI121037 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI COLLINS, JAMES J · 2016 to 2025
$4.4M
Supporting flood recovery in rural, mountainous areas through health systems knowledge exchange and fine-scale healthcare utilization data analysisR61NR021961 · NINR · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI GOHLKE, JULIA M · 2025 to 2025
$791k
NIH HHS R01AI121037NINR NIH HHS R61 NR021961
6 · The paper itself

Abstract

Parasitic helminths are master manipulators of host immunity. Their strategy is complex and involves the release of excreted/secreted products, including extracellular vesicles (EVs). The protein and miRNA contents of EVs have been characterised for many parasitic helminths but, despite reports suggesting the importance of EV surface carbohydrate structures (glycans) in the interactions with target cells and thus subsequent effector functions, little is known about parasite EV glycomics. Using lectin microarrays, we identified several lectins that exhibit strong adhesion to

Indexed as

exosomesextracellular vesiclesglycanshelminthslectin histochemistrylectin microarrayschistosomessecretomesialic acid

Identifiers

PMID34832557
PMCPMC8617790
OpenAlexW3210167013

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.