Evidence map›Paper›PMID 34832430›Full record

ArticleMaterials (Basel, Switzerland)2021

Additives Imparting Antimicrobial Properties to Acrylic Bone Cements.

Alina Robu, Aurora Antoniac, Elena Grosu, Eugeniu Vasile, Anca Daniela Raiciu, Florin Iordache, Vasile Iulian Antoniac, Julietta V Rau, Viktoriya G Yankova, Lia Mara Ditu and 1 more

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 3 countries.

Alina RobuFaculty of Material Science and Engineering, UniversityPolitehnica of Bucharest, 313 Splaiul Independentei Street, District 6, 060042 Bucharest, Romania.
Aurora AntoniacFaculty of Material Science and Engineering, UniversityPolitehnica of Bucharest, 313 Splaiul Independentei Street, District 6, 060042 Bucharest, Romania.
Elena GrosuFaculty of Material Science and Engineering, UniversityPolitehnica of Bucharest, 313 Splaiul Independentei Street, District 6, 060042 Bucharest, Romania.
Eugeniu VasileFaculty of Applied Chemistry and Material Science, University Politehnica of Bucharest, 313 Splaiul Independentei Street, District 6, 060042 Bucharest, Romania.
Anca Daniela RaiciuFaculty of Pharmacy, Titu Maiorescu University, 22 Dambovnicului Street, District 4, 040441 Bucharest, Romania.
Florin IordacheFaculty of Veterinary Medicine, University of Agronomic Sciences and Veterinary Medicine Bucharest, 59 Bulevardul Marasti, 050097 Bucharest, Romania.ORCID 0000-0002-5366-6792
Vasile Iulian AntoniacFaculty of Material Science and Engineering, UniversityPolitehnica of Bucharest, 313 Splaiul Independentei Street, District 6, 060042 Bucharest, Romania.ORCID 0000-0003-0112-3494
Julietta V RauIstituto di Struttura della Materia, Consiglio Nazionale delle Ricerche (ISM-CNR), Via del Fosso del Cavaliere 100, 00133 Rome, Italy.ORCID 0000-0002-7953-1853
Viktoriya G YankovaInstitute of Pharmacy, Department of Analytical, Physical and Colloid Chemistry, I.M. Sechenov First Moscow State Medical University, 8 Trubetskaya Street, Build. 2, 119991 Moscow, Russia.
Lia Mara DituFaculty of Biology, University of Bucharest, Intrarea Portocalelor Street, no. 1-3, 060101 Bucharest, Romania.ORCID 0000-0002-6593-255X
Vicentiu SaceleanuFaculty of Medicine, University Lucian Blaga Sibiu, 2A Lucian Blaga Street, 550169 Sibiu, Romania.ORCID 0000-0002-4997-2690
Universitatea Națională de Știință și Tehnologie Politehnica București · ROSechenov University · RUAcademia Oamenilor de Știință din România · ROLucian Blaga University of Sibiu · ROTitu Maiorescu University · ROUniversity of Agronomic Sciences and Veterinary Medicine of Bucharest · ROUniversity of Bucharest · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PMMA bone cements are mainly used to fix implanted prostheses and are introduced as a fluid mixture, which hardens over time. The problem of infected prosthesis could be solved due to the development of some new antibacterial bone cements. In this paper, we show the results obtained to develop four different modified PMMA bone cements by using antimicrobial additives, such as gentamicin, peppermint oil incorporated in hydroxyapatite, and silver nanoparticles incorporated in a ceramic glass matrix (2 and 4%). The structure and morphology of the modified bone cements were investigated by SEM and EDS. We perform experimental measurements on wettability, hydration degree, and degradation degree after immersion in simulated body fluid. The cytotoxicity was evaluated by MTT assay using the human MG-63 cell line. Antimicrobial properties were checked against standard strains

Indexed as

antimicrobial propertiesgentamicinpeppermint essential oilPMMA bone cementssilver nanoparticles

Identifiers

PMID34832430
PMCPMC8622877
OpenAlexW3216012445

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.