ReviewMaterials (Basel, Switzerland)2021
Discoloration Potential of Biodentine: A Systematic Review.
Review in Materials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Clinical and radiographic outcomes of pulpotomy materials in permanent teeth: a systematic review of calcium hydroxide, MTA, biodentine, and iRoot BP plus.BMC oral health · 2025Pooled it
- Effect of diode laser pretreatment on dentin thickness and discoloration in deep caries treated with biodentine: a randomized clinical trial.Scientific reports · 2026Trial
- Cost efficiency of calcium silicate and glass ionomer cements in pulpotomies of first mandibular primary molars.Journal of clinical and experimental dentistry · 2026Article
- Therapy and material choices in pulp exposure among public dentists in Norway.Acta odontologica Scandinavica · 2026Article
- Advanced Platelet-Rich Fibrin Plus Sealed Exclusively with Glass Ionomer Cement: Setting a New Standard for Healing, Aesthetics and Predictive Modelling in Regenerative Endodontics.Materials (Basel, Switzerland) · 2025Article
- Management of External Root Resorption following Replantation After Accidental Tooth Extraction Using Regenerative Endodontic Procedures: A Case Report.Journal of clinical and experimental dentistry · 2025Article
- Evaluating the impact of material type and blood contamination on tooth color stability post external cervical root resorption repair: a spectrophotometric study.BMC oral health · 2025Article
- Bioceramics in Endodontics: Limitations and Future Innovations-A Review.Dentistry journal · 2025Review
- Clinical applications and classification of calcium silicate-based cements based on their history and evolution: a narrative review.Clinical oral investigations · 2025Review
- Effect of Vital Pulp Therapy Biomaterials on Tooth Discolouration: A Review of the Literature.International journal of biomaterials · 2025Review
- Evaluation of the genotoxicity, cytotoxicity, and bioactivity of calcium silicate-based cements.BMC oral health · 2024Article
- Management of Maxillary Incisors With Middle-Third Root Perforation: A Case Report.Case reports in dentistry · 2024Article
- Partial Pulpotomy in Young Permanent Teeth: A Systematic Review and Meta-Analysis.Children (Basel, Switzerland) · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this systematic review is to investigate the teeth discoloration potential of Biodentine. An electronic search in six databases (PubMed, Cochrane Library, LILACS, SCIELO, Web of Science, and Scopus) was conducted by three independent reviewers to identify eligible articles. The following search terms were used: ((discolo*, staining potential, color, colour, or spectrophotomet*), (teeth or tooth), and (Biodentine)). Methodology following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analysis) guidelines was adopted for this investigation. At the end of the selection process, 30 articles were identified as eligible, of which 14 in vitro studies were included in this systematic review. Nine of the included studies evaluated the discoloration potential of Biodentine in the presence of blood. Within the limitations of this review, teeth discoloration using Biodentine is highly expected when material is placed in direct contact with blood during dental procedures. In the absence of blood, Biodentine causes less teeth color changes than MTA-based materials, but it is still unclear what clinically relevant results could be expected regarding the discoloration frequency and intensity induced by Biodentine.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.