Evidence map›Paper›PMID 34832210›Full record

ArticleMaterials (Basel, Switzerland)2021

Assessment of the Effect of Structural Modification of Ibuprofen on the Penetration of Ibuprofen from Pentravan

Paula Ossowicz-Rupniewska, Anna Nowak, Joanna Klebeko, Ewa Janus, Wiktoria Duchnik, Urszula Adamiak-Giera, Łukasz Kucharski, Piotr Prowans, Jan Petriczko, Norbert Czapla and 3 more

Abstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Enhanced encapsulation and membrane retention ofInternational journal of pharmaceutics: X · 2026
    Article
  2. Biological activities and safety assessment ofInternational journal of pharmaceutics: X · 2026
    Article
  3. Article
  4. Efficacy of lidocaine-prilocaine combined with amitriptyline orJournal of dental anesthesia and pain medicine · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Evaluation of theFrontiers in pharmacology · 2023
    Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Paula Ossowicz-RupniewskaDepartment of Chemical Organic Technology and Polymeric Materials, Faculty of Chemical Technology and Engineering, West Pomeranian University of Technology in Szczecin, Piastów Avenue 42, PL-71065 Szczecin, Poland.ORCID 0000-0002-2362-1809
Anna NowakDepartment of Cosmetic and Pharmaceutical Chemistry, Pomeranian Medical University in Szczecin, Powstańców Wielkopolskich Avenue 72, PL-70111 Szczecin, Poland.ORCID 0000-0002-4287-6751
Joanna KlebekoDepartment of Chemical Organic Technology and Polymeric Materials, Faculty of Chemical Technology and Engineering, West Pomeranian University of Technology in Szczecin, Piastów Avenue 42, PL-71065 Szczecin, Poland.ORCID 0000-0002-3176-5511
Ewa JanusDepartment of Chemical Organic Technology and Polymeric Materials, Faculty of Chemical Technology and Engineering, West Pomeranian University of Technology in Szczecin, Piastów Avenue 42, PL-71065 Szczecin, Poland.ORCID 0000-0002-7396-9424
Wiktoria DuchnikDepartment of Cosmetic and Pharmaceutical Chemistry, Pomeranian Medical University in Szczecin, Powstańców Wielkopolskich Avenue 72, PL-70111 Szczecin, Poland.
Urszula Adamiak-GieraDepartment of Pharmacokinetics and Therapeutic Drug Monitoring, Pomeranian Medical University in Szczecin, PL-70111 Szczecin, Poland.
Łukasz KucharskiDepartment of Cosmetic and Pharmaceutical Chemistry, Pomeranian Medical University in Szczecin, Powstańców Wielkopolskich Avenue 72, PL-70111 Szczecin, Poland.
Piotr ProwansDepartment of Plastic, Endocrine and General Surgery, Pomeranian Medical University in Szczecin, PL-72010 Police, Poland.
Jan PetriczkoDepartment of Plastic, Endocrine and General Surgery, Pomeranian Medical University in Szczecin, PL-72010 Police, Poland.ORCID 0000-0002-1616-7564
Norbert CzaplaDepartment of Plastic, Endocrine and General Surgery, Pomeranian Medical University in Szczecin, PL-72010 Police, Poland.
Piotr BargielDepartment of Plastic, Endocrine and General Surgery, Pomeranian Medical University in Szczecin, PL-72010 Police, Poland.
Marta MarkowskaDepartment of Plastic, Endocrine and General Surgery, Pomeranian Medical University in Szczecin, PL-72010 Police, Poland.
Adam KlimowiczDepartment of Cosmetic and Pharmaceutical Chemistry, Pomeranian Medical University in Szczecin, Powstańców Wielkopolskich Avenue 72, PL-70111 Szczecin, Poland.

Funding

National Centre for Research and Development LIDER/53/0225/L-11/19/NCBR/2020
6 · The paper itself

Abstract

The effect of transdermal vehicle (Pentravan

Indexed as

Franz cell diffusionhuman skinincreasing drug permeabilityPentravan®Strat-M®structural modification of ibuprofentransdermal delivery system

Identifiers

PMID34832210
PMCPMC8624710

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.