Evidence map›Paper›PMID 34832066›Full record

ArticleMembranes2021

AN69 Filter Membranes with High Ultrafiltration Rates during Continuous Venovenous Hemofiltration Reduce Mortality in Patients with Sepsis-Induced Multiorgan Dysfunction Syndrome.

Kuo-Hua Lee, Shuo-Ming Ou, Ming-Tsun Tsai, Wei-Cheng Tseng, Chih-Yu Yang, Yao-Ping Lin, Der-Cherng Tarng

Open access · goldAbstract read
In one paragraph

Article in Membranes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Observational
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kuo-Hua LeeDivision of Nephrology, Department of Medicine, Taipei Veterans General Hospital, Taipei 11217, Taiwan.ORCID 0000-0002-6314-8788
Shuo-Ming OuDivision of Nephrology, Department of Medicine, Taipei Veterans General Hospital, Taipei 11217, Taiwan.
Ming-Tsun TsaiDivision of Nephrology, Department of Medicine, Taipei Veterans General Hospital, Taipei 11217, Taiwan.ORCID 0000-0002-8597-4132
Wei-Cheng TsengDivision of Nephrology, Department of Medicine, Taipei Veterans General Hospital, Taipei 11217, Taiwan.ORCID 0000-0002-6940-9651
Chih-Yu YangDivision of Nephrology, Department of Medicine, Taipei Veterans General Hospital, Taipei 11217, Taiwan.ORCID 0000-0001-9899-3159
Yao-Ping LinDivision of Nephrology, Department of Medicine, Taipei Veterans General Hospital, Taipei 11217, Taiwan.
Der-Cherng TarngDivision of Nephrology, Department of Medicine, Taipei Veterans General Hospital, Taipei 11217, Taiwan.ORCID 0000-0001-9017-2081
National Yang Ming Chiao Tung University · TW

Funding

Ministry of Science and Technology 109-2314-B-010-056-MY3, 109-2314-B-075-066, 110-2314-B-075-008Taipei Veterans General Hospital V108D42-004-MY3-2, V109D50-001-MY3-1, V109C-114, and V109B-016Taiwan Poison Control FPC-110-003
6 · The paper itself

Abstract

Polyacrylonitrile (AN69) filter membranes adsorb cytokines during continuous venovenous hemofiltration (CVVH). Although high-volume hemofiltration has shown limited benefits, the dose-effect relationship in CVVH with AN69 membranes on severe sepsis remains undetermined. This multi-centered study enrolled 266 patients with sepsis-induced multiorgan dysfunction syndrome (MODS) who underwent CVVH with AN69 membranes between 2014 and 2015. We investigated the effects of ultrafiltration rates (UFR) on mortality. We categorized patients that were treated with UFR of 20-25 mL/kg/h as the standard UFR group (

Indexed as

blood purificationcritical medicineintensive care unitmultiple organ failure

Identifiers

PMID34832066
PMCPMC8618352
OpenAlexW3210765177

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.