Evidence map›Paper›PMID 34831913›Full record

ArticleInternational journal of environmental research and public health2021

Associations between Brain Reserve Proxies and Clinical Progression in Alzheimer's Disease Dementia.

Hyung-Jun Yoon, Seung-Gon Kim, Sang Hoon Kim, Jong Inn Woo, Eun Hyun Seo, For The Alzheimer's Disease Neuroimaing Initiative

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hyung-Jun YoonDepartment of Neuropsychiatry, College of Medicine, Chosun University/Chosun University Hospital, Gwangju 61452, Korea.ORCID 0000-0003-3087-8853
Seung-Gon KimDepartment of Neuropsychiatry, College of Medicine, Chosun University/Chosun University Hospital, Gwangju 61452, Korea.
Sang Hoon KimDepartment of Neuropsychiatry, College of Medicine, Chosun University/Chosun University Hospital, Gwangju 61452, Korea.
Jong Inn WooDepartment of Neuropsychiatry, College of Medicine, Seoul National University Hospital, Seoul 03080, Korea.
Eun Hyun SeoPremedical Science, College of Medicine, Chosun University, Gwangju 61452, Korea.
For The Alzheimer's Disease Neuroimaing Initiative

Funding

Alzheimer's Disease Neuroimaging Initiative - SupplementU01AG024904 · NIA · NORTHERN CALIFORNIA INSTITUTE RES &EDUC · PI WEINER, MICHAEL W · 2004 to 2015
$121.0M
NIA NIH HHS U01 AG024904
6 · The paper itself

Abstract

The purpose of this study was to investigate whether brain and cognitive reserves were associated with the clinical progression of AD dementia. We included participants with AD dementia from the Alzheimer's Disease Neuroimaging Initiative, provided they were followed up at least once, and candidate proxies for cognitive (education for early-life reserve and Adult Reading Test for late-life reserve) or brain reserve (intracranial volume [ICV] for early-life reserve and the composite value of [

Indexed as

Alzheimer DiseaseCognitive DysfunctionCognitive ReserveAdultBrainDisease ProgressionHumansNeuroimagingPositron-Emission TomographyAlzheimer’s diseasebrain reservecerebral glucose metabolismclinical progressioncognitive reservedementia

Identifiers

PMID34831913
PMCPMC8625916

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.