Evidence map›Paper›PMID 34831884›Full record

Trial reportInternational journal of environmental research and public health2021

Exposure to a Multilevel, Multicomponent Obesity Prevention Intervention (OPREVENT2) in Rural Native American Communities: Variability and Association with Change in Diet Quality.

Michelle Estradé, Ellen J I van Dongen, Angela C B Trude, Lisa Poirier, Sheila Fleischhacker, Caroline R Wensel, Leslie C Redmond, Marla Pardilla, Jacqueline Swartz, Margarita S Treuth and 1 more

Abstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Interventions to prevent obesity in children aged 2 to 4 years old.The Cochrane database of systematic reviews · 2025
    Pooled it
  3. Interventions to prevent obesity in children aged 5 to 11 years old.The Cochrane database of systematic reviews · 2024
    Pooled it
  4. Article
  5. Design of theFrontiers in public health · 2024
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Michelle EstradéDepartment of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.ORCID 0000-0002-3972-3471
Ellen J I van DongenDepartment of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.
Angela C B TrudeDepartment of Pediatrics, University of Maryland School of Medicine, Baltimore, MD 21201, USA.ORCID 0000-0002-2881-1089
Lisa PoirierDepartment of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.
Sheila FleischhackerGeorgetown University Law Center, Washington, DC 20001, USA.ORCID 0000-0001-6503-1439
Caroline R WenselDepartment of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.ORCID 0000-0001-6233-2922
Leslie C RedmondSchool of Allied Health, University of Alaska Anchorage, Anchorage, AK 99508, USA.
Marla PardillaDepartment of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.
Jacqueline SwartzDepartment of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.
Margarita S TreuthDepartment of Kinesiology, School of Pharmacy and Health Professions, University of Maryland Eastern Shore, Princess Anne, MD 21853, USA.
Joel GittelsohnDepartment of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.ORCID 0000-0003-2761-3280

Funding

Multilevel program and policies to reduce chronic disease for American IndiansR01HL122150 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI GITTELSOHN, JOEL · 2015 to 2019
$3.3M
NHLBI NIH HHS R01 HL122150
6 · The paper itself

Abstract

The OPREVENT2 obesity prevention trial was a multilevel multicomponent (MLMC) intervention implemented in rural Native American communities in the Midwest and Southwest U.S. Intervention components were delivered through local food stores, worksites, schools, community action coalitions, and by social and community media. Due to the complex nature of MLMC intervention trials, it is useful to assess participants' exposure to each component of the intervention in order to assess impact. In this paper, we present a detailed methodology for evaluating participant exposure to MLMC intervention, and we explore how exposure to the OPREVENT2 trial impacted participant diet quality. There were no significant differences in total exposure score by age group, sex, or geographic region, but exposure to sub-components of the intervention differed significantly by age group, sex, and geographical region. Participants with the highest overall exposure scores showed significantly more improvement in diet quality from baseline to follow up compared to those who were least exposed to the intervention. Improved diet quality was also significantly positively associated with several exposure sub-components. While evaluating exposure to an entire MLMC intervention is complex and imperfect, it can provide useful insight into an intervention's impact on key outcome measures, and it can help identify which components of the intervention were most effective.

Indexed as

ExerciseHealth PromotionAmerican Indian or Alaska NativeDietHumansObesitydiet qualityexposurehealthy eating indexMLMC interventionNative American

Identifiers

PMID34831884
PMCPMC8621011

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.